Sorbitol Dosage
Medically reviewed by Drugs.com. Last updated on Nov 25, 2024.
Applies to the following strengths: 70%; 3.3%; 3%
Usual Adult Dose for:
Usual Pediatric Dose for:
Additional dosage information:
Usual Adult Dose for Constipation
Oral: 30 to 150 mL (70% solution) once.
Rectal: 120 mL (25% to 30% solution) as a rectal enema once.
Usual Pediatric Dose for Constipation
2 to 11 years:
Oral: 2 mL/kg (70% solution) once.
Rectal: 30 to 60 mL (25% to 30% solution) as a rectal enema once.
Greater than or equal to 12 years:
Oral: 30 to 150 mL (70% solution) once.
Rectal: 120 mL (25% to 30% solution) as a rectal enema once.
Renal Dose Adjustments
Data not available
Liver Dose Adjustments
Data not available
Precautions
The use of sorbitol is contraindicated in patients with anuria. Sorbitol should not be used in patients with suspected or documented fructose intolerance. Sorbitol should not given by injection.
Sudden severe abdominal bloating and diarrhea have been reported in patients ingesting sorbitol.
Solutions for urologic irrigation should be used with caution in patients with severe cardiopulmonary or renal dysfunction.
Irrigating fluids used during transurethral prostatectomy have been demonstrated to enter the systemic circulation in relatively large volumes; thus sorbitol irrigating solution must be regarded as a systemic agent. Absorption of large amounts of fluids containing sorbitol may significantly alter cardiopulmonary and renal dynamics. Appropriate patient monitoring should be conducted due to the possibility of fluid overload. If fluid overload occurs, intensive fluid and electrolyte management should be initiated. Monitoring of fluid and electrolyte levels beyond the acute phase may be necessary due to the possibility of delayed fluid absorption.
Hyperglycemia from metabolism of absorbed sorbitol may be observed in patients with diabetes mellitus.
The cardiovascular status, especially of the patient with cardiac disease, should be carefully monitored before and during transurethral resection of the prostate when using 3% sorbitol urologic irrigating solution, because the quantity of fluid absorbed into the systemic circulation by opened prostatic veins may produce significant expansion of the intravascular fluid and lead to fulminating congestive heart failure.
Shift of sodium free intracellular fluid into the extracellular compartment, following systemic absorption could lower serum concentration and aggravate preexisting hyponatremia.
Excessive loss of water and electrolytes may lead to serious imbalances. With continuous use of solution, loss of water may occur in excess of electrolytes, producing hypernatremia.
Sustained diuresis that results from transurethral irrigation with sorbitol irrigating solutions could obscure and intensify inadequate hydration or hypovolemia.
Dialysis
Data not available
More about sorbitol
- Check interactions
- Compare alternatives
- Pricing & coupons
- Reviews (1)
- Side effects
- During pregnancy
- Drug class: laxatives
- En español
Patient resources
Related treatment guides
See also:
MiraLAX
MiraLAX (polyethylene glycol) is used as a laxative to treat occasional constipation or irregular ...
Colace
Colace makes bowel movements softer and is used to treat or prevent constipation. Includes Colace ...
Ozempic
Learn about Ozempic (semaglutide) for type 2 diabetes treatment, weight management, cardiovascular ...
Linzess
Linzess (linaclotide) is used to treat chronic idiopathic constipation, irritable bowel syndrome ...
Dulcolax
Dulcolax (bisacodyl) is a laxative used to treat constipation. Includes Dulcolax side effects ...
Metamucil
Metamucil is used for constipation, dietary fiber supplementation, irritable bowel syndrome
Polyethylene glycol 3350
Polyethylene glycol 3350 systemic is used for bowel preparation, constipation, constipation, acute ...
Magnesium oxide
Magnesium oxide systemic is used for constipation, duodenal ulcer, GERD, hypomagnesemia ...
Senna
Senna is a laxative is used treat constipation. Includes senna side effects, interactions and ...
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.