Sarecycline Dosage

Medically reviewed by Drugs.com. Last updated on Apr 24, 2025.

Usual Adult Dose for Acne

Weight 33 to 54 kg: 60 mg orally once a day
Weight 55 to 84 kg: 100 mg orally once a day
Weight 85 to 136 kg: 150 mg orally once a day

Use: For the treatment of inflammatory lesions of nonnodular moderate to severe acne vulgaris

Usual Pediatric Dose for Acne

9 years or older:

• Weight 33 to 54 kg: 60 mg orally once a day
• Weight 55 to 84 kg: 100 mg orally once a day
• Weight 85 to 136 kg: 150 mg orally once a day

Use: For the treatment of inflammatory lesions of nonnodular moderate to severe acne vulgaris

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Precautions

CONTRAINDICATIONS:
Shown hypersensitivity to any of the tetracyclines

Safety and efficacy have not been established in patients younger than 9 years; tetracycline-class antibiotics are not recommended for use in patients younger than 8 years (due to potential for tooth discoloration).

Consult WARNINGS section for additional precautions.

Dialysis

Data not available

Other Comments

Administration advice:

• Administer with or without food.
• Administer with plenty of fluid to reduce risk of esophageal irritation and ulceration.

Storage requirements:

• Store at 20C to 25C (68F to 77F); excursions permitted to 15C to 30C (59F to 86F).
• Protect from moisture and excessive heat.

General:

• If no improvement observed after 12 weeks, treatment with this drug should be reassessed.
• Efficacy beyond 12 weeks and safety beyond 12 months have not been established.
• This drug has not been evaluated in the treatment of infections.
• To reduce the development of drug-resistant organisms and maintain efficacy of other antibacterial agents, this drug should be used only as indicated.

Patient advice:

• Read the US FDA-approved patient labeling (Patient Information).
• Drink plenty of fluids.
• Avoid missing doses and complete the entire course of therapy.
• If watery or bloody stools develop, seek medical attention.
• If headache or blurred vision occur, seek medical attention.
• This drug may cause CNS symptoms; ability to drive vehicles or operate hazardous machinery may be affected; seek medical assistance for persistent CNS symptoms.
• Minimize or avoid exposure to natural or artificial sunlight during therapy; if you must be outdoors while using this drug, wear loose-fitting clothes that protect skin from sun exposure and discuss other sun protection methods with physician.

Frequently asked questions

• What are the most common skin conditions? (with photos)
• What type of acne is Seysara (sarecycline) used to treat?

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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