Sarecycline Dosage
Medically reviewed by Drugs.com. Last updated on May 4, 2023.
Applies to the following strengths: 60 mg; 100 mg; 150 mg
Usual Adult Dose for:
Usual Pediatric Dose for:
Additional dosage information:
Usual Adult Dose for Acne
Weight 33 to 54 kg: 60 mg orally once a day
Weight 55 to 84 kg: 100 mg orally once a day
Weight 85 to 136 kg: 150 mg orally once a day
Use: For the treatment of inflammatory lesions of nonnodular moderate to severe acne vulgaris
Usual Pediatric Dose for Acne
9 years or older:
- Weight 33 to 54 kg: 60 mg orally once a day
- Weight 55 to 84 kg: 100 mg orally once a day
- Weight 85 to 136 kg: 150 mg orally once a day
Use: For the treatment of inflammatory lesions of nonnodular moderate to severe acne vulgaris
Renal Dose Adjustments
Data not available
Liver Dose Adjustments
Data not available
Precautions
CONTRAINDICATIONS:
Shown hypersensitivity to any of the tetracyclines
Safety and efficacy have not been established in patients younger than 9 years; tetracycline-class antibiotics are not recommended for use in patients younger than 8 years (due to potential for tooth discoloration).
Consult WARNINGS section for additional precautions.
Dialysis
Data not available
Other Comments
Administration advice:
- Administer with or without food.
- Administer with plenty of fluid to reduce risk of esophageal irritation and ulceration.
Storage requirements:
- Store at 20C to 25C (68F to 77F); excursions permitted to 15C to 30C (59F to 86F).
- Protect from moisture and excessive heat.
General:
- If no improvement observed after 12 weeks, treatment with this drug should be reassessed.
- Efficacy beyond 12 weeks and safety beyond 12 months have not been established.
- This drug has not been evaluated in the treatment of infections.
- To reduce the development of drug-resistant organisms and maintain efficacy of other antibacterial agents, this drug should be used only as indicated.
Patient advice:
- Read the US FDA-approved patient labeling (Patient Information).
- Drink plenty of fluids.
- Avoid missing doses and complete the entire course of therapy.
- If watery or bloody stools develop, seek medical attention.
- If headache or blurred vision occur, seek medical attention.
- This drug may cause CNS symptoms; ability to drive vehicles or operate hazardous machinery may be affected; seek medical assistance for persistent CNS symptoms.
- Minimize or avoid exposure to natural or artificial sunlight during therapy; if you must be outdoors while using this drug, wear loose-fitting clothes that protect skin from sun exposure and discuss other sun protection methods with physician.
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