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Seysara

Generic Name: sarecycline (SAR e SYE kleen)
Brand Names: Seysara

Medically reviewed by P. Thornton, DipPharm Last updated on Jun 4, 2019.

What is Seysara?

Seysara (sarecycline) is a tetracycline antibiotic.

Seysara is a prescription medicine used to treat severe acne vulgaris in adults and children who are at least 9 years old.

Seysara should not be used for the treatment or prevention of infections.

Important Information

Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.

Before taking this medicine

You should not take Seysara if you are allergic to sarecycline or similar antibiotics such as demeclocycline, doxycycline, minocycline, tetracycline, or tigecycline.

To make sure this medicine is safe for you, tell your doctor if you have:

Taking Seysara during pregnancy may affect tooth and bone development in the unborn baby. Taking this medicine during the last half of pregnancy can cause permanent tooth discoloration later in the baby's life. Tell your doctor if you are pregnant or if you become pregnant.

Sarecycline can pass into breast milk and may affect bone and tooth development in a nursing infant. Do not breast-feed while you are taking sarecycline.

Seysara is not approved for use by anyone younger than 9 years old. This medicine can cause permanent yellowing or graying of the teeth in children.

How should I take Seysara?

Take Seysara exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets.

You may take Seysara with or without food.

To help prevent ulcers or irritation in your esophagus, take this medicine with a full glass of water

Use this medicine for the full prescribed length of time, even if your symptoms quickly improve. Skipping doses can increase your risk of infection that is resistant to medication. Seysara will not treat a viral infection such as the flu or a common cold.

Store at room temperature away from moisture and heat.

Seysara dosing information

Usual Adult Dose for Acne:

Weight 33 to 54 kg: 60 mg orally once a day
Weight 55 to 84 kg: 100 mg orally once a day
Weight 85 to 136 kg: 150 mg orally once a day

Use: For the treatment of inflammatory lesions of nonnodular moderate to severe acne vulgaris

Usual Pediatric Dose for Acne:

9 years or older:
-Weight 33 to 54 kg: 60 mg orally once a day
-Weight 55 to 84 kg: 100 mg orally once a day
-Weight 85 to 136 kg: 150 mg orally once a day

Use: For the treatment of inflammatory lesions of nonnodular moderate to severe acne vulgaris

What happens if I miss a dose?

Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while taking Seysara?

Avoid driving or hazardous activity until you know how Seysara will affect you. Your reactions could be impaired.

Antibiotic medicines can cause diarrhea, which may be a sign of a new infection. If you have diarrhea that is watery or bloody, call your doctor before using anti-diarrhea medicine.

Seysara could make you sunburn more easily. Avoid sunlight or tanning beds. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors.

Seysara side effects

Get emergency medical help if you have signs of an allergic reaction to Seysara: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • a light-headed feeling, like you might pass out;

  • a spinning sensation; or

  • increased pressure inside the skull - severe headaches, ringing in your ears, vision problems, pain behind your eyes.

Common Seysara side effects may include nausea.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Seysara?

Tell your doctor about all your other medicines, especially:

This list is not complete. Other drugs may interact with sarecycline, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Seysara only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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