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Paromomycin Dosage

Medically reviewed by Drugs.com. Last updated on April 4, 2019.

Applies to the following strengths: 250 mg

Usual Adult Dose for Amebiasis

25 to 35 mg/kg/day orally in 3 divided doses with meals for 5 to 10 days

Comments:
-This drug is not effective in extraintestinal amebiasis.

Use: For intestinal amebiasis (acute and chronic)

Usual Adult Dose for Hepatic Coma

4 g/day orally in divided doses (at regular intervals) for 5 to 6 days

Use: As adjunctive therapy, for management of hepatic coma

Usual Adult Dose for Dientamoeba fragilis

US CDC Recommendations: 25 to 35 mg/kg/day orally in 3 divided doses for 7 days

Comments:
-Recommended as a regimen to treat infection due to Dientamoeba fragilis
-Current guidelines should be consulted for additional information.

Usual Pediatric Dose for Amebiasis

25 to 35 mg/kg/day orally in 3 divided doses with meals for 5 to 10 days

Comments:
-This drug is not effective in extraintestinal amebiasis.

Use: For intestinal amebiasis (acute and chronic)

Usual Pediatric Dose for Dientamoeba fragilis

American Academy of Pediatrics Recommendations: 25 to 35 mg/kg/day orally in 3 divided doses for 7 days

Comments:
-Recommended as a regimen to treat infection due to D fragilis
-Current guidelines should be consulted for additional information.

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Precautions

CONTRAINDICATIONS:
History of hypersensitivity reactions to the active component or any of the ingredients; intestinal obstruction

Consult WARNINGS section for additional precautions.

Dialysis

Data not available

Other Comments

Storage requirements:
-Store at 20C to 25C (68F to 77F) in tight container.
-Protect from moisture.

General:
-To reduce the development of drug-resistant organisms and maintain effective therapy, this drug should be used only to treat or prevent infections proven or strongly suspected to be caused by susceptible bacteria.
-Culture and susceptibility information should be considered when selecting/modifying antibacterial therapy or, if no data are available, local epidemiology and susceptibility patterns may be considered when selecting empiric therapy.

Patient advice:
-Avoid missing doses and complete the entire course of therapy.
-Consult physician for medical advice about side effects.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.