Medically reviewed by Drugs.com. Last updated on Dec 2, 2021.
Recommended Testing Prior to LYSTEDA Administration
Prior to prescribing LYSTEDA, exclude endometrial pathology that can be associated with heavy menstrual bleeding.
The recommended dosage of LYSTEDA for patients with normal renal function is 1300 mg orally three times daily (3900 mg/day) for a maximum of 5 days during monthly menstruation. LYSTEDA may be administered with or without food. Swallow tablets whole; do not chew or break apart.
Dosage Recommendations in Patients with Renal Impairment
The recommended dosage (for a maximum of 5 days during monthly menstruation) in patients with renal impairment with serum creatinine concentration higher than 1.4 mg/dL is described in Table 1.
(maximum of 5 days
|Above 1.4 and ≤ 2.8||1300 mg two times a day||2600 mg|
|Above 2.8 and ≤ 5.7||1300 mg once a day||1300 mg|
|Above 5.7||650 mg once a day||650 mg|
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