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Famvir Dosage

Generic name: FAMCICLOVIR 125mg
Dosage form: tablet, film coated

Medically reviewed by Drugs.com. Last updated on Sep 17, 2018.

FAMVIR may be taken with or without food.

2.1 Dosing Recommendation in Immunocompetent Adult Patients

Herpes labialis (cold sores): The recommended dosage of FAMVIR for the treatment of recurrent herpes labialis is 1500 mg as a single dose. Therapy should be initiated at the first sign or symptom of herpes labialis (e.g., tingling, itching, burning, pain, or lesion).

Genital herpes:

Recurrent episodes: The recommended dosage of FAMVIR for the treatment of recurrent episodes of genital herpes is 1000 mg twice daily for 1 day. Therapy should be initiated at the first sign or symptom of a recurrent episode (e.g., tingling, itching, burning, pain, or lesion).

Suppressive therapy: The recommended dosage of FAMVIR for chronic suppressive therapy of recurrent episodes of genital herpes is 250 mg twice daily.

Herpes zoster (shingles): The recommended dosage of FAMVIR for the treatment of herpes zoster is 500 mg every 8 hours for 7 days. Therapy should be initiated as soon as herpes zoster is diagnosed.

2.2 Dosing Recommendation in HIV-Infected Adult Patients

Recurrent orolabial or genital herpes: The recommended dosage of FAMVIR for the treatment of recurrent orolabial or genital herpes in HIV-infected patients is 500 mg twice daily for 7 days. Therapy should be initiated at the first sign or symptom of a recurrent episode (e.g., tingling, itching, burning, pain, or lesion).

2.3 Dosing Recommendation in Patients with Renal Impairment

Dosage recommendations for adult patients with renal impairment are provided in Table 1 [see Use in Specific Populations (8.6), Clinical Pharmacology (12.3)].

Table 1: Dosage Recommendations for Adult Patients with Renal Impairment
Indication and Normal Dosage
Regimen
Creatinine Clearance
(mL/min)
Adjusted Dosage
Regimen Dose (mg)
Dosing Interval
Single-Day Dosing Regimens
Recurrent Genital Herpes
1000 mg every 12 hours for 1 day
≥ 60 1000 every 12 hours for 1 day
40-59 500 every 12 hours for 1 day
20-39 500 single dose
< 20 250 single dose
HD* 250 single dose following
dialysis
Recurrent Herpes Labialis
1500 mg single dose
≥ 60 1500 single dose
40-59 750 single dose
20-39 500 single dose
< 20 250 single dose
HD* 250 single dose following
dialysis
Multiple-Day Dosing Regimens
Herpes Zoster
500 mg every 8 hours
≥ 60 500 every 8 hours
40-59 500 every 12 hours
20-39 500 every 24 hours
< 20 250 every 24 hours
HD* 250 following each dialysis
Suppression of Recurrent
Genital Herpes
250 mg every 12 hours
≥ 40 250 every 12 hours
20-39 125 every 12 hours
< 20 125 every 24 hours
HD* 125 following each dialysis
Recurrent Orolabial
or Genital Herpes
in HIV-Infected Patients
500 mg every 12 hours
≥ 40 500 every 12 hours
20-39 500 every 24 hours
< 20 250 every 24 hours
HD* 250 following each dialysis

*Hemodialysis

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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