Dartisla ODT Dosage

Important Dosing Information

• Patients receiving the 2 mg dosage strength of another oral tablet dosage form of glycopyrrolate may be switched to the 1.7 mg dosage strength of DARTISLA ODT [see Dosage Forms and Strengths (3) and Clinical Pharmacology (12.3)].

• DARTISLA ODT is not recommended for patients in whom a lower dosage strength of another oral glycopyrrolate product (e.g., tablet strength of 1 mg) is appropriate for initial or maintenance treatment because the dosage strength of DARTISLA ODT may exceed the recommended initial and maintenance dosage of other oral glycopyrrolate products.

Recommended Dosage

• The recommended dosage of DARTISLA ODT is 1.7 mg given two or three times daily administered on top of the tongue. Allow the tablet to disintegrate and swallow without water [see Clinical Pharmacology (12.3)].
• The maximum recommended daily dosage of DARTISLA ODT is 6.8 mg.
• Administer DARTISLA ODT at least one hour before or two hours after food [see Clinical Pharmacology (12.3)].
• Use the lowest effective dosage of glycopyrrolate to control symptoms. Switch patients who can be titrated to a lower dose of oral glycopyrrolate to another oral tablet dosage form of glycopyrrolate.

Administration Instructions

• Use dry hands when opening the blister card and do not open the blister until ready to administer.
• Open the package and peel back the foil on the blister to expose the tablet and gently remove from the blister. Do not push the tablet through the foil.
• Do not break or cut the tablet.
• Immediately place the tablet on the tongue, allow it to disintegrate, and swallow without water.