Dapsone Topical Dosage
Medically reviewed by Drugs.com. Last updated on May 2, 2025.
Applies to the following strengths: 5%; 7.5%
Usual Adult Dose for:
Usual Pediatric Dose for:
Additional dosage information:
Usual Adult Dose for Acne
Topical gel 5%: Apply approximately a pea-sized amount in a thin layer to the acne affected areas twice a day.
Topical gel 7.5%: Apply approximately a pea-sized amount in a thin layer to the entire face (and other affected areas) once a day.
Use: For the topical treatment of acne vulgaris
Usual Pediatric Dose for Acne
12 years or older:
- Topical gel 5%: Apply approximately a pea-sized amount in a thin layer to the acne affected areas twice a day.
- Topical gel 7.5%: Apply approximately a pea-sized amount in a thin layer to the entire face (and other affected areas) once a day.
Use: For the topical treatment of acne vulgaris
Renal Dose Adjustments
No data available
Liver Dose Adjustments
No data available
Precautions
CONTRAINDICATIONS: None
Safety and efficacy have not been established in patients younger than 12 years; the topical gel 5% is not recommended for use in these patients.
Consult WARNINGS section for additional precautions.
Dialysis
No data available
Other Comments
Administration advice:
- For topical use only; not for oral, ophthalmic, or intravaginal use
- Gently wash and pat dry the skin before using this drug.
- Rub in gently and completely.
- Wash hands after using this drug.
Storage requirements:
- Store at 20C to 25C (68F to 77F); excursions permitted to 15C to 30C (59F to 86F).
- Protect from freezing.
General:
- The topical gel 5% is gritty; drug substance particles may be seen in the gel.
- Therapy should be reassessed if there is no improvement after 12 weeks.
- Coadministration with benzoyl peroxide may cause temporary localized yellow or orange discoloration of the skin and facial hair.
Patient advice:
- Read the US FDA-approved patient labeling (Patient Information).
- Stop this drug and seek immediate medical attention if cyanosis develops.
- Seek medical attention if signs/symptoms suggesting hemolytic anemia develop.
- Do not apply to eyes, mouth, or mucous membranes.
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.