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Dapsone Topical Dosage

Medically reviewed by Drugs.com. Last updated on May 2, 2022.

Applies to the following strengths: 5%; 7.5%

Usual Adult Dose for:

Usual Pediatric Dose for:

Additional dosage information:

Usual Adult Dose for Acne

Topical gel 5%: Apply approximately a pea-sized amount in a thin layer to the acne affected areas twice a day.
Topical gel 7.5%: Apply approximately a pea-sized amount in a thin layer to the entire face (and other affected areas) once a day.

Use: For the topical treatment of acne vulgaris

Usual Pediatric Dose for Acne

12 years or older:

  • Topical gel 5%: Apply approximately a pea-sized amount in a thin layer to the acne affected areas twice a day.
  • Topical gel 7.5%: Apply approximately a pea-sized amount in a thin layer to the entire face (and other affected areas) once a day.

Use: For the topical treatment of acne vulgaris

Renal Dose Adjustments

No data available

Liver Dose Adjustments

No data available

Precautions

CONTRAINDICATIONS: None

Safety and efficacy have not been established in patients younger than 12 years; the topical gel 5% is not recommended for use in these patients.

Consult WARNINGS section for additional precautions.

Dialysis

No data available

Other Comments

Administration advice:

  • For topical use only; not for oral, ophthalmic, or intravaginal use
  • Gently wash and pat dry the skin before using this drug.
  • Rub in gently and completely.
  • Wash hands after using this drug.

Storage requirements:
  • Store at 20C to 25C (68F to 77F); excursions permitted to 15C to 30C (59F to 86F).
  • Protect from freezing.

General:
  • The topical gel 5% is gritty; drug substance particles may be seen in the gel.
  • Therapy should be reassessed if there is no improvement after 12 weeks.
  • Coadministration with benzoyl peroxide may cause temporary localized yellow or orange discoloration of the skin and facial hair.

Patient advice:
  • Read the US FDA-approved patient labeling (Patient Information).
  • Stop this drug and seek immediate medical attention if cyanosis develops.
  • Seek medical attention if signs/symptoms suggesting hemolytic anemia develop.
  • Do not apply to eyes, mouth, or mucous membranes.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.