brynovin Dosage
Generic name: SITAGLIPTIN 25mg in 1mL
Dosage form: oral solution
Drug class: Dipeptidyl peptidase 4 inhibitors
Medically reviewed by Drugs.com. Last updated on Jan 2, 2025.
Recommended Dosage and Administration
Measure the BRYNOVIN dose using a calibrated oral syringe or oral dosing cup scored using metric units of measurements (i.e., mL).
The recommended dosage of BRYNOVIN is 100 mg (4 mL) taken orally once daily. BRYNOVIN can be taken with or without food.
Recommendations for Use in Renal Impairment
Assess renal function prior to initiation of BRYNOVIN and periodically thereafter.
For patients with an estimated glomerular filtration rate (eGFR) greater than or equal to 45 mL/min/1.73 m2 to less than 90 mL/min/1.73 m2, no dosage adjustment for BRYNOVIN is required.
For patients with moderate renal impairment (eGFR greater than or equal to 30 mL/min/1.73 m2 to less than 45 mL/min/1.73 m2), the dosage of BRYNOVIN is 50 mg (2 mL) once daily.
For patients with severe renal impairment (eGFR less than 30 mL/min/1.73 m2) or with end-stage renal disease (ESRD) requiring hemodialysis or peritoneal dialysis, the dosage of BRYNOVIN is 25 mg (1 mL) once daily. BRYNOVIN may be administered without regard to the timing of dialysis.
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