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BioThrax Dosage

Generic name: BACILLUS ANTHRACIS STRAIN V770-NP1-R ANTIGENS 100ug in 1mL
Dosage form: injection, suspension
Drug class: Bacterial vaccines

Medically reviewed by Drugs.com. Last updated on May 6, 2025.

For intramuscular or subcutaneous injection only.

Dose

Each dose is 0.5 mL.

Pre-Exposure Prophylaxis:

Schedule

Route of Administration

Dosing Schedule

Primary Series

Intramuscular

0,1, and 6 months

Booster Series

Intramuscular

6 and 12 months after completion of the primary series and at 12-month intervals thereafter

In persons who are at risk for hematoma formation following intramuscular injection, BioThrax may be administered by the subcutaneous route. The pre-exposure prophylaxis schedule for BioThrax administered subcutaneously is 0, 2, 4 weeks, and 6 months with booster doses at 6 and 12 months after completion of the primary series and at 12-month intervals thereafter.

The optimal schedule for catch up of missed or delayed booster doses is unknown.

Post-Exposure Prophylaxis:

Schedule

Route of Administration

Dosing Schedule

Primary Series

Subcutaneous

0, 2, and 4 weeks post-exposure combined with antimicrobial therapy

Administration

Shake the vial thoroughly to ensure that the suspension is homogeneous during withdrawal. Parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration, whenever solution and container permit. If either of these conditions exists, do not administer the vaccine.

Administer pre-exposure prophylaxis vaccinations intramuscularly into the deltoid muscle. If pre-exposure prophylaxis requires subcutaneous administration, administer over the deltoid muscle. Administer post-exposure prophylaxis vaccinations subcutaneously over the deltoid muscle.

Do not mix with any other product in the syringe.

See also:

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.