BioThrax Dosage
Generic name: BACILLUS ANTHRACIS STRAIN V770-NP1-R ANTIGENS 100ug in 1mL
Dosage form: injection, suspension
Drug class: Bacterial vaccines
Medically reviewed by Drugs.com. Last updated on May 6, 2025.
For intramuscular or subcutaneous injection only.
Dose
Each dose is 0.5 mL.
Pre-Exposure Prophylaxis:
Schedule |
Route of Administration |
Dosing Schedule |
Primary Series |
Intramuscular |
0,1, and 6 months |
Booster Series |
Intramuscular |
6 and 12 months after completion of the primary series and at 12-month intervals thereafter |
In persons who are at risk for hematoma formation following intramuscular injection, BioThrax may be administered by the subcutaneous route. The pre-exposure prophylaxis schedule for BioThrax administered subcutaneously is 0, 2, 4 weeks, and 6 months with booster doses at 6 and 12 months after completion of the primary series and at 12-month intervals thereafter.
The optimal schedule for catch up of missed or delayed booster doses is unknown.
Post-Exposure Prophylaxis:
Schedule |
Route of Administration |
Dosing Schedule |
Primary Series |
Subcutaneous |
0, 2, and 4 weeks post-exposure combined with antimicrobial therapy |
Administration
Shake the vial thoroughly to ensure that the suspension is homogeneous during withdrawal. Parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration, whenever solution and container permit. If either of these conditions exists, do not administer the vaccine.
Administer pre-exposure prophylaxis vaccinations intramuscularly into the deltoid muscle. If pre-exposure prophylaxis requires subcutaneous administration, administer over the deltoid muscle. Administer post-exposure prophylaxis vaccinations subcutaneously over the deltoid muscle.
Do not mix with any other product in the syringe.
More about Biothrax (anthrax vaccine adsorbed)
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Further information
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