Benzoyl Peroxide / Tretinoin Topical Dosage

Medically reviewed by Drugs.com. Last updated on Jun 23, 2025.

Usual Adult Dose for Acne

Apply a thin layer to the affected area once a day

Comments:

• This drug is for topical use only.
• The affected area should be thoroughly washed and dried before application.

Use: For the topical treatment of acne vulgaris in adults

Usual Pediatric Dose for Acne

Apply a thin layer to the affected area once a day

Comments:

• This drug is for topical use only.
• The affected area should be thoroughly washed and dried before application.

Use: For the topical treatment of acne vulgaris in pediatric patients 9 years of age and older

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Precautions

CONTRAINDICATIONS:

• Patients with a history of hypersensitivity reaction to benzoyl peroxide or any components.

Safety and efficacy have not been established in patients younger than 9 years.

Consult WARNINGS section for additional precautions.

Dialysis

Data not available

Other Comments

Administration advice:

• This drug is for topical use only.
• Advise patients to wash hands immediately after application.
• Avoid contact with the eyes, lips, paranasal creases, and mucous membranes.

Storage requirements:

• Refrigerate at 2C to 8C (36F to 46F) until dispensed to the patient.
• Store at room temperature 20C to 25C (68F to 77F) after dispensed.
• Discard 12 weeks after date of dispensing or 30 days after first opening, whichever is sooner.
• Do not freeze.

Monitoring:

• Excessive skin irritation
• Sunburns/increased photosensitivity

Patient advice:

• Advice patients on using appropriate sun protection while on therapy.
• Instruct patients to wash the affected area with a mild, non-medicated soap and pat the area dry before application.
• Inform patients that the product may bleach hair or colored fabric.
• Instruct patients to store at room temperature and to discard 12 weeks after date of dispensing or 30 days after first opening, whichever is sooner.
• Advise the patient to use a moisturizer for irritation.
• instruct patient to discontinue treatment immediately and seek medical help in case of serious hypersensitivity reaction.
• Advise patients to minimize unprotected exposure to sunlight and sunlamps.
• Advise patients to wash hands immediately after application.

See also:

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer