Aspruzyo Sprinkle Dosage
Generic name: RANOLAZINE 500mg
Dosage form: oral granules
Drug class: Antianginal agents
Medically reviewed by Drugs.com. Last updated on Jan 29, 2025.
Dosing Information
Initiate ASPRUZYO Sprinkle dosing at 500 mg orally twice daily and increase to 1000 mg orally twice daily, as needed, based on clinical symptoms.
The maximum recommended daily dose of ASPRUZYO Sprinkle is 1000 mg twice daily.
If a dose of ASPRUZYO Sprinkle is missed, take the prescribed dose at the next scheduled time; do not double the next dose.
Directions for use with soft food (e.g., applesauce and yogurt)
- Sprinkle granules on one tablespoonful of soft food and consume immediately.
- Do not crush or chew the granules.
Direction for nasogastric and gastric tube administration
Nasogastric (NG) tube:Add the content of a sachet to a plastic catheter tip syringe and add 50 mL of water. Gently shake the syringe for approximately 15 seconds. Promptly deliver through a 12 French or larger NG tube. Ensure no granules are left in the syringe. Rinse with additional water (about 15 mL) if needed.
Gastrostomy/Gastric (G) tube: Add the content of a sachet to a plastic catheter tip syringe and add 30 mL of water. Gently shake the syringe for approximately 15 seconds. Promptly deliver through a 12 French or larger G-tube. Rinse with 20 mL of water in the syringe. Ensure no granules are left in the syringe. Rinse with additional water (about 15 mL) if needed.
Dose Modification
Dose adjustments may be needed when ASPRUZYO Sprinkle is taken in combination with other drugs.Limit the maximum dose of ASPRUZYO Sprinkle to 500 mg twice daily in patients on moderate CYP3A inhibitors such as diltiazem, verapamil, and erythromycin. Use of ASPRUZYO Sprinkle with strong CYP3A inhibitors and CYP3A inducers is contraindicated.
More about Aspruzyo Sprinkle (ranolazine)
- Check interactions
- Compare alternatives
- Pricing & coupons
- Drug images
- Side effects
- During pregnancy
- Drug class: antianginal agents
- En español
Patient resources
Other brands
Professional resources
Other brands
Related treatment guides
See also:
Bisoprolol
Bisoprolol belongs to a group of drugs called beta-blockers and is used to treat hypertension (high ...
Isosorbide mononitrate
Isosorbide mononitrate is used to prevent angina attacks (chest pain) by dilating blood vessels ...
Ozempic
Learn about Ozempic (semaglutide) for type 2 diabetes treatment, weight management, cardiovascular ...
Diltiazem
Diltiazem is used to treat high blood pressure, angina and certain heart rhythm disorders. Included ...
Nifedipine
Nifedipine is used to lower hypertension (high blood pressure) and to treat angina (chest pain) ...
Enoxaparin
Enoxaparin systemic is used for acute coronary syndrome, angina, deep vein thrombosis, deep vein ...
Heparin
Heparin injection is used to treat and prevent blood clots in the veins, arteries, or lungs. Learn ...
Atenolol
Atenolol is used to treat angina (chest pain) and hypertension (high blood pressure). Learn about ...
Nitroglycerin
Nitroglycerin systemic is used for anal fissure and fistula, angina, angina pectoris prophylaxis ...
Propranolol
Propranolol is a beta-blocker that is used to treat tremors, chest pain, high blood pressure, heart ...
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.