Acetaminophen / Phenyltoloxamine Dosage
Medically reviewed by Drugs.com. Last updated on Jun 6, 2023.
Applies to the following strengths: 325 mg-30 mg; 600 mg-66 mg; 650 mg-50 mg; 500 mg-50 mg; 650 mg-60 mg; 500 mg-30 mg; 500 mg-30 mg/15 mL; 500 mg-60 mg; 500 mg-55 mg; 635 mg-55 mg
Usual Adult Dose for:
Usual Pediatric Dose for:
Additional dosage information:
Usual Adult Dose for Cold Symptoms
Acetaminophen-phenyltoloxamine 325 mg-30 mg oral tablet:
1 or 2 tablets orally every 4 hours not to exceed 8 tablets daily.
Acetaminophen-phenyltoloxamine 500 mg-50 mg oral tablet:
1/2 to 1 tablet orally every 4 hours not to exceed 5 tablets daily.
Acetaminophen-phenyltoloxamine 500 mg-55 mg oral tablet:
1 or 2 tablets orally every 4 hours not to exceed 8 tablets daily.
Acetaminophen-phenyltoloxamine 600 mg-66 mg oral tablet, extended release:
1 to 2 tablets orally every 8 to 12 hours not to exceed 6 tablets daily.
Acetaminophen-phenyltoloxamine 635 mg-55 mg oral tablet and Acetaminophen-phenyltoloxamine 650 mg-60 mg oral tablet:
1/2 to 1 tablet orally every 6 hours not to exceed 4 tablets daily. Not to exceed 10 days use.
Usual Adult Dose for Influenza
Acetaminophen-phenyltoloxamine 325 mg-30 mg oral tablet:
1 or 2 tablets orally every 4 hours not to exceed 8 tablets daily.
Acetaminophen-phenyltoloxamine 500 mg-50 mg oral tablet:
1/2 to 1 tablet orally every 4 hours not to exceed 5 tablets daily.
Acetaminophen-phenyltoloxamine 500 mg-55 mg oral tablet:
1 or 2 tablets orally every 4 hours not to exceed 8 tablets daily.
Acetaminophen-phenyltoloxamine 600 mg-66 mg oral tablet, extended release:
1 to 2 tablets orally every 8 to 12 hours not to exceed 6 tablets daily.
Acetaminophen-phenyltoloxamine 635 mg-55 mg oral tablet and Acetaminophen-phenyltoloxamine 650 mg-60 mg oral tablet:
1/2 to 1 tablet orally every 6 hours not to exceed 4 tablets daily. Not to exceed 10 days use.
Usual Adult Dose for Pain
Acetaminophen-phenyltoloxamine 325 mg-30 mg oral tablet:
1 or 2 tablets orally every 4 hours not to exceed 8 tablets daily.
Acetaminophen-phenyltoloxamine 500 mg-50 mg oral tablet:
1/2 to 1 tablet orally every 4 hours not to exceed 5 tablets daily.
Acetaminophen-phenyltoloxamine 500 mg-55 mg oral tablet:
1 or 2 tablets orally every 4 hours not to exceed 8 tablets daily.
Acetaminophen-phenyltoloxamine 600 mg-66 mg oral tablet, extended release:
1 to 2 tablets orally every 8 to 12 hours not to exceed 6 tablets daily.
Acetaminophen-phenyltoloxamine 635 mg-55 mg oral tablet and Acetaminophen-phenyltoloxamine 650 mg-60 mg oral tablet:
1/2 to 1 tablet orally every 6 hours not to exceed 4 tablets daily. Not to exceed 10 days use.
Usual Adult Dose for Headache
Acetaminophen-phenyltoloxamine 325 mg-30 mg oral tablet:
1 or 2 tablets orally every 4 hours not to exceed 8 tablets daily.
Acetaminophen-phenyltoloxamine 500 mg-50 mg oral tablet:
1/2 to 1 tablet orally every 4 hours not to exceed 5 tablets daily.
Acetaminophen-phenyltoloxamine 500 mg-55 mg oral tablet:
1 or 2 tablets orally every 4 hours not to exceed 8 tablets daily.
Acetaminophen-phenyltoloxamine 600 mg-66 mg oral tablet, extended release:
1 to 2 tablets orally every 8 to 12 hours not to exceed 6 tablets daily.
Acetaminophen-phenyltoloxamine 635 mg-55 mg oral tablet and Acetaminophen-phenyltoloxamine 650 mg-60 mg oral tablet:
1/2 to 1 tablet orally every 6 hours not to exceed 4 tablets daily. Not to exceed 10 days use.
Usual Pediatric Dose for Cold Symptoms
Acetaminophen-phenyltoloxamine 325 mg-30 mg oral tablet:
12 years or older: 1 or 2 tablets orally every 4 hours not to exceed 8 tablets daily.
Acetaminophen-phenyltoloxamine 500 mg-50 mg oral tablet:
6 to 11 years: 1/2 tablet orally every 4 hours not to exceed 2.5 tablets daily.
12 years or older: 1/2 to 1 tablet orally every 4 hours not to exceed 5 tablets daily.
Acetaminophen-phenyltoloxamine 500 mg-55 mg oral tablet:
6 to 11 years: 1/2 to 1 tablet orally every 4 hours not to exceed 4 tablets daily.
12 years or older: 1 or 2 tablets orally every 4 hours not to exceed 8 tablets daily.
Acetaminophen-phenyltoloxamine 600 mg-66 mg oral tablet, extended release:
6 to 11 years: 1/2 to 1 tablet orally every 12 hours not to exceed 2 tablets daily.
12 years or older: 1 to 2 tablets orally every 8 to 12 hours not to exceed 6 tablets daily.
Acetaminophen-phenyltoloxamine 635 mg-55 mg oral tablet and Acetaminophen-phenyltoloxamine 650 mg-60 mg oral tablet:
6 to 11 years: 1/2 tablet orally every 6 hours not to exceed 2 tablets daily. Not to exceed 5 days use.
12 years or older: 1/2 to 1 tablet orally every 6 hours not to exceed 4 tablets daily. Not to exceed 10 days use.
Usual Pediatric Dose for Influenza
Acetaminophen-phenyltoloxamine 325 mg-30 mg oral tablet:
12 years or older: 1 or 2 tablets orally every 4 hours not to exceed 8 tablets daily.
Acetaminophen-phenyltoloxamine 500 mg-50 mg oral tablet:
6 to 11 years: 1/2 tablet orally every 4 hours not to exceed 2.5 tablets daily.
12 years or older: 1/2 to 1 tablet orally every 4 hours not to exceed 5 tablets daily.
Acetaminophen-phenyltoloxamine 500 mg-55 mg oral tablet:
6 to 11 years: 1/2 to 1 tablet orally every 4 hours not to exceed 4 tablets daily.
12 years or older: 1 or 2 tablets orally every 4 hours not to exceed 8 tablets daily.
Acetaminophen-phenyltoloxamine 600 mg-66 mg oral tablet, extended release:
6 to 11 years: 1/2 to 1 tablet orally every 12 hours not to exceed 2 tablets daily.
12 years or older: 1 to 2 tablets orally every 8 to 12 hours not to exceed 6 tablets daily.
Acetaminophen-phenyltoloxamine 635 mg-55 mg oral tablet and Acetaminophen-phenyltoloxamine 650 mg-60 mg oral tablet:
6 to 11 years: 1/2 tablet orally every 6 hours not to exceed 2 tablets daily. Not to exceed 5 days use.
12 years or older: 1/2 to 1 tablet orally every 6 hours not to exceed 4 tablets daily. Not to exceed 10 days use.
Usual Pediatric Dose for Pain
Acetaminophen-phenyltoloxamine 325 mg-30 mg oral tablet:
12 years or older: 1 or 2 tablets orally every 4 hours not to exceed 8 tablets daily.
Acetaminophen-phenyltoloxamine 500 mg-50 mg oral tablet:
6 to 11 years: 1/2 tablet orally every 4 hours not to exceed 2.5 tablets daily.
12 years or older: 1/2 to 1 tablet orally every 4 hours not to exceed 5 tablets daily.
Acetaminophen-phenyltoloxamine 500 mg-55 mg oral tablet:
6 to 11 years: 1/2 to 1 tablet orally every 4 hours not to exceed 4 tablets daily.
12 years or older: 1 or 2 tablets orally every 4 hours not to exceed 8 tablets daily.
Acetaminophen-phenyltoloxamine 600 mg-66 mg oral tablet, extended release:
6 to 11 years: 1/2 to 1 tablet orally every 12 hours not to exceed 2 tablets daily.
12 years or older: 1 to 2 tablets orally every 8 to 12 hours not to exceed 6 tablets daily.
Acetaminophen-phenyltoloxamine 635 mg-55 mg oral tablet and Acetaminophen-phenyltoloxamine 650 mg-60 mg oral tablet:
6 to 11 years: 1/2 tablet orally every 6 hours not to exceed 2 tablets daily. Not to exceed 5 days use.
12 years or older: 1/2 to 1 tablet orally every 6 hours not to exceed 4 tablets daily. Not to exceed 10 days use.
Usual Pediatric Dose for Headache
Acetaminophen-phenyltoloxamine 325 mg-30 mg oral tablet:
12 years or older: 1 or 2 tablets orally every 4 hours not to exceed 8 tablets daily.
Acetaminophen-phenyltoloxamine 500 mg-50 mg oral tablet:
6 to 11 years: 1/2 tablet orally every 4 hours not to exceed 2.5 tablets daily.
12 years or older: 1/2 to 1 tablet orally every 4 hours not to exceed 5 tablets daily.
Acetaminophen-phenyltoloxamine 500 mg-55 mg oral tablet:
6 to 11 years: 1/2 to 1 tablet orally every 4 hours not to exceed 4 tablets daily.
12 years or older: 1 or 2 tablets orally every 4 hours not to exceed 8 tablets daily.
Acetaminophen-phenyltoloxamine 600 mg-66 mg oral tablet, extended release:
6 to 11 years: 1/2 to 1 tablet orally every 12 hours not to exceed 2 tablets daily.
12 years or older: 1 to 2 tablets orally every 8 to 12 hours not to exceed 6 tablets daily.
Acetaminophen-phenyltoloxamine 635 mg-55 mg oral tablet and Acetaminophen-phenyltoloxamine 650 mg-60 mg oral tablet:
6 to 11 years: 1/2 tablet orally every 6 hours not to exceed 2 tablets daily. Not to exceed 5 days use.
12 years or older: 1/2 to 1 tablet orally every 6 hours not to exceed 4 tablets daily. Not to exceed 10 days use.
Renal Dose Adjustments
Data not available
Liver Dose Adjustments
Use with caution in patients with liver disease. Chronic use of acetaminophen is not recommended in patients with liver disease.
Precautions
Patients who consume three or more alcohol containing drinks per day should be informed to consult with their physician for advice on when and how to take acetaminophen. Chronic, heavy alcohol users may be at increased risk of liver damage when taking more than recommended dosages.
Patients and adults taking care of children should be advised to consult with their doctor before continuing to use acetaminophen if symptoms of illness worsen. Although rare, there is the possibility of acetaminophen intoxication on chronic use of the drug, and the symptoms seen during the first phase of intoxication (nausea, vomiting, anorexia, malaise, and diaphoresis) may trigger the use of more doses.
Patients should be warned of the sedative effects of phenyltoloxamine, and advised not to take this drug with alcohol.
Phenyltoloxamine should be used with caution in patients with narrow-angle glaucoma, stenosing peptic ulcer, pyloroduodenal obstruction, prostatic hypertrophy, or bladder-neck obstructions, increased intraocular pressure, hyperthyroidism, cardiovascular disease, or hypertension.
Dialysis
Data not available
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