Vismodegib Disease Interactions
There is 1 disease interaction with vismodegib:
Hedgehog Pathway Inhibitors (Includes Vismodegib) ↔ Musculoskeletal Disorders
Moderate Potential Hazard, Moderate plausibility
Applies to: History - Musculoskeletal Disorder
Musculoskeletal adverse reactions, which may be accompanied by serum creatine kinase elevations have been reported with the use of drugs that inhibit the hedgehog pathway. It is recommended to obtain serum creatine kinase levels and renal function tests prior to initiating therapy, periodically during treatment, and as clinically indicated. Care should be taken when prescribing these agents to patients presenting musculoskeletal pain or myalgia. Temporary dose interruption or discontinuation of therapy may be required based on the severity of musculoskeletal adverse reactions.
vismodegib drug Interactions
There are 120 drug interactions with vismodegib
More about vismodegib
- Vismodegib Side Effects
- During Pregnancy
- Dosage Information
- Drug Interactions
- En Español
- Drug class: hedgehog pathway inhibitors
Related treatment guides
Drug Interaction Classification
|Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.|
|Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.|
|Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.|
|No information available.|
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