Skip to Content

Unoprostone ophthalmic Disease Interactions

There is 1 disease interaction with unoprostone ophthalmic:


Unoprostone ophthalmic (Includes unoprostone ophthalmic) ↔ renal/liver disease

Moderate Potential Hazard, Moderate plausibility. Applies to: Renal Dysfunction, Liver Disease

Unoprostone isopropyl is hydrolyzed by esterases in the cornea and conjunctival epithelium to the active free acid form, which is absorbed systemically and metabolized by the liver. The metabolites are eliminated by the kidney. Unoprostone isopropyl has not been adequately studied in the treatment of patients with impaired renal and/or hepatic function. Therapy with unoprostone isopropyl ophthalmic solution should be administered cautiously in such patients.


  1. "Product Information. Rescula (unoprostone ophthalmic)" Ciba Vision Ophthalmics, Duluth, GA.

Unoprostone ophthalmic drug interactions

There are 9 drug interactions with unoprostone ophthalmic

Drug Interaction Classification

The classifications below are a general guideline only. It is difficult to determine the relevance of a particular drug interaction to any individual given the large number of variables.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No information available.

Do not stop taking any medications without consulting your healthcare provider.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.