Ubrogepant Disease Interactions
There are 2 disease interactions with ubrogepant.
Ubrogepant (applies to ubrogepant) hepatic dysfunction
Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Liver Disease
Care should be exercised when using ubrogepant in patients with severe hepatic impairment. Dose adjustment is recommended for these patients. No dose adjustment is recommended for patients with mild or moderate hepatic impairment.
Ubrogepant (applies to ubrogepant) renal impairment
Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Renal Dysfunction
It is recommended to avoid the use of ubrogepant in patients with end-stage renal disease (CrCl <15 mL/min). No dosing recommendations can be made for these patients. A dose adjustment is recommended for patients with severe renal impairment (CrCl 15-29 mL/min). No dose adjustments are recommended for patients with mild or moderate renal impairment.
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Ubrogepant drug interactions
There are 248 drug interactions with ubrogepant.
Ubrogepant alcohol/food interactions
There is 1 alcohol/food interaction with ubrogepant.
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- Drug class: CGRP inhibitors
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
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