Selexipag Disease Interactions
There are 2 disease interactions with selexipag:
Selexipag (Includes selexipag) ↔ liver impairment
Moderate Potential Hazard, Moderate plausibility. Applies to: Liver Disease
Liver impairment can increase exposure to selexipag and its metabolites. No dose adjustment is necessary in patients with mild impairment, but a once a day regimen is recommended in patients with moderate hepatic impairment. There is no experience with selexipag in patients with severe hepatic impairment and its use should be avoided in these patients.
Selexipag (Includes selexipag) ↔ renal impairment
Moderate Potential Hazard, Moderate plausibility. Applies to: Renal Dysfunction
No adjustment to the dosing regimen of selexipag is required in patients with estimated glomerular filtration rate > 15 mL/min/1.73m2. There is no clinical experience with selexipag in patients with glomerular filtration rates lower than this, or in patients undergoing dialysis.
Selexipag drug interactions
There are 512 drug interactions with selexipag
Selexipag alcohol/food interactions
There is 1 alcohol/food interaction with selexipag
More about selexipag
- Selexipag Side Effects
- During Pregnancy
- Dosage Information
- Drug Interactions
- En Español
- 11 Reviews
- Drug class: agents for pulmonary hypertension
Related treatment guides
Drug Interaction Classification
|Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.|
|Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.|
|Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.|
|No information available.|
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