Romiplostim Disease Interactions
There are 3 disease interactions with romiplostim.
Romiplostim (applies to romiplostim) leukemia
Major Potential Hazard, Moderate plausibility. Applicable conditions: Myelodysplastic Disease
Progression from myelodysplastic syndromes (MDS) to acute myelogenous leukemia (AML) has been observed in clinical trials with romiplostim. This drug is not indicated for the treatment of thrombocytopenia due to MDS or any other cause other than chronic ITP.
Romiplostim (applies to romiplostim) hepatic impairment
Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Liver Disease
No clinical studies with romiplostim have been conducted in patients with hepatic impairment.
Romiplostim (applies to romiplostim) renal impairment
Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Renal Dysfunction
No clinical studies with romiplostim have been conducted in patients with renal impairment.
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Romiplostim drug interactions
There are 10 drug interactions with romiplostim.
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- During pregnancy
- Drug class: platelet-stimulating agents
- Breastfeeding
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
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