Depade (naltrexone) Disease Interactions
There is 1 disease interaction with Depade (naltrexone):
Opiate Antagonists (Includes Depade) ↔ Hepatic/Renal Dysfunction
Moderate Potential Hazard, Moderate plausibility
Applies to: Renal Dysfunction, Liver Disease
Opiate antagonists are metabolized by the liver (naltrexone to an active metabolite) and eliminated by the kidney. Hepatic and renal impairment may reduce the metabolism and clearance of opiate antagonists. Dosage adjustment for single dose administration is not necessary, however, repeated doses in patients with hepatic and/or renal dysfunction may require adjustment.
- "Product Information. Revex (nalmefene)." Ohmeda Pharmaceutical Products Division, Liberty Corner, NJ.
- "Product Information. Narcan (naloxone)." DuPont Pharmaceuticals, Wilmington, DE.
Depade (naltrexone) drug Interactions
There are 552 drug interactions with Depade (naltrexone)
Depade (naltrexone) alcohol/food Interactions
There is 1 alcohol/food interaction with Depade (naltrexone)
More about Depade (naltrexone)
- Depade Side Effects
- During Pregnancy or Breastfeeding
- Dosage Information
- Drug Interactions
- Drug class: antidotes
Related treatment guides
Drug Interaction Classification
|Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.|
|Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.|
|Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.|
|No information available.|
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