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Imiquimod topical Disease Interactions

There are 2 disease interactions with imiquimod topical:

Moderate

Imiquimod Topical (Includes Imiquimod topical) ↔ Eczema

Moderate Potential Hazard, High plausibility

Applies to: Eczema

Imiquimod may exacerbate inflammatory conditions of the skin. Local reactions are commonly associated with the use of imiquimod and may extend beyond the application site onto the surrounding skin. These reactions include erythema, edema, vesicles, erosion/ulceration, weeping/exudate, flaking/scaling/dryness, and scabbing/crusting. Therapy with topical imiquimod should be avoided or used with caution in patients with eczematous conditions.

References

  1. "Product Information. Aldara (imiquimod topical)." 3M Pharmaceuticals, St. Paul, MN.
Moderate

Imiquimod Topical (Includes Imiquimod topical) ↔ Sunburn

Moderate Potential Hazard, High plausibility

Applies to: Sunburn

The use of imiquimod may be associated with heightened sunburn susceptibility. Patients with sunburn should be cautioned not to use imiquimod until fully recovered. Exposure to sunlight, including sunlamps, should be avoided or minimized during treatment, and protective clothing (e.g., hat) is recommended when exposure is unavoidable.

References

  1. "Product Information. Aldara (imiquimod topical)." 3M Pharmaceuticals, St. Paul, MN.

Drug Interaction Classification

The classifications below are a general guideline only. It is difficult to determine the relevance of a particular drug interaction to any individual given the large number of variables.

Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.

Do not stop taking any medications without consulting your healthcare provider.

Disclaimer: Every effort has been made to ensure that the information provided by Multum is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. Multum's information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill, knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Multum Information Services, Inc. does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. Copyright 2000-2016 Multum Information Services, Inc. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse, or pharmacist.

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