Imiquimod topical Disease Interactions

Imiquimod may exacerbate inflammatory conditions of the skin. Local reactions are commonly associated with the use of imiquimod and may extend beyond the application site onto the surrounding skin. These reactions include erythema, edema, vesicles, erosion/ulceration, weeping/exudate, flaking/scaling/dryness, and scabbing/crusting. Therapy with topical imiquimod should be avoided or used with caution in patients with eczematous conditions.

The use of imiquimod may be associated with heightened sunburn susceptibility. Patients with sunburn should be cautioned not to use imiquimod until fully recovered. Exposure to sunlight, including sunlamps, should be avoided or minimized during treatment, and protective clothing (e.g., hat) is recommended when exposure is unavoidable.