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Iloprost Disease Interactions

There are 2 disease interactions with iloprost.

Major

Iloprost (applies to iloprost) hypotension

Major Potential Hazard, Moderate plausibility.

Iloprost should not be initiated in patients with systolic blood pressure below 85 mmHg. The risk of syncope in association with physical exertion can occur in pulmonary arterial hypertension and the occurrence may reflect a therapeutic gap or insufficient efficacy. The need to adjust dose or change therapy should be considered. It is recommended to monitor vital signs when initiating treatment with iloprost in patients at risk.

References

  1. (2005) "Product Information. Ventavis (iloprost)." Actelion Pharmaceuticals US Inc
Moderate

Iloprost (applies to iloprost) bronchospasm

Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Pulmonary Impairment

Iloprost can induce bronchospasm and may be more severe or frequent in patients with history of hyperreactive airways. Close monitoring is recommended when using iloprost in patients with chronic obstructive pulmonary disease, severe asthma, or with acute pulmonary infections.

References

  1. (2005) "Product Information. Ventavis (iloprost)." Actelion Pharmaceuticals US Inc

Iloprost drug interactions

There are 294 drug interactions with iloprost.

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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