Finasteride Disease Interactions
There are 2 disease interactions with finasteride:
5-alpha-reductase inhibitors (applies to finasteride) liver disease
Moderate Potential Hazard, Moderate plausibility.
Finasteride and dutasteride are extensively metabolized by the liver. Therapy with these drugs should be administered cautiously in patients with liver disease as exposure could be higher.
- "Product Information. Propecia (finasteride)." Merck & Co, Inc, West Point, PA.
Finasteride (applies to finasteride) urinary obstruction
Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Urinary Tract Obstruction
Patients with large residual urinary volume and/or severely diminished urinary flow should be carefully monitored for obstructive uropathy. These patients may not be candidates for finasteride therapy.
Finasteride drug interactions
There are 22 drug interactions with finasteride
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- Drug class: 5-alpha-reductase inhibitors
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Drug Interaction Classification
|Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.|
|Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.|
|Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.|
|No interaction information available.|
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