Finasteride Disease Interactions
There are 2 disease interactions with finasteride:
5-alpha-reductase inhibitors (Includes finasteride) ↔ liver disease
Moderate Potential Hazard, Moderate plausibility. Applies to: Liver Disease
Finasteride and dutasteride are extensively metabolized by the liver. Therapy with these drugs should be administered cautiously in patients with liver disease as exposure could be higher.
- "Product Information. Propecia (finasteride)." Merck & Co, Inc, West Point, PA.
Finasteride (Includes finasteride) ↔ urinary obstruction
Moderate Potential Hazard, Moderate plausibility. Applies to: Urinary Tract Obstruction
Patients with large residual urinary volume and/or severely diminished urinary flow should be carefully monitored for obstructive uropathy. These patients may not be candidates for finasteride therapy.
Finasteride drug interactions
There are 16 drug interactions with finasteride
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- Drug class: 5-alpha-reductase inhibitors
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Drug Interaction Classification
|Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.|
|Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.|
|Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.|
|No information available.|
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