Ampyra (dalfampridine) Disease Interactions
There are 2 disease interactions with Ampyra (dalfampridine):
Dalfampridine (Includes Ampyra) ↔ renal impairment
Severe Potential Hazard, Moderate plausibility. Applies to: Renal Dysfunction
Dalfampridine is contraindicated in patients with moderate or severe renal impairment (CrCl<=50 mL/min). Dalfampridine is eliminated through the kidneys primarily as unchanged drug and its clearance is decreased in patients with renal impairment and is significantly correlated with creatinine clearance.
Dalfampridine (Includes Ampyra) ↔ seizures
Severe Potential Hazard, Moderate plausibility. Applies to: Seizures
Dalfampridine is contraindicated in patients with a history of seizures. Dalfampridine can cause seizures and it is recommended to permanently discontinue treatment in patients who have a seizure while on treatment.
Ampyra (dalfampridine) drug interactions
There are 59 drug interactions with Ampyra (dalfampridine)
More about Ampyra (dalfampridine)
- Ampyra Side Effects
- During Pregnancy
- Dosage Information
- Drug Images
- Drug Interactions
- Compare Alternatives
- Support Group
- Pricing & Coupons
- En Español
- 60 Reviews
- Generic Availability
- Drug class: miscellaneous central nervous system agents
- FDA Alerts (1)
Related treatment guides
Drug Interaction Classification
|Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.|
|Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.|
|Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.|
|No information available.|
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