Cromolyn Disease Interactions
There is 1 disease interaction with cromolyn:
Cromolyn (Includes Cromolyn) ↔ Renal/Liver Disease
Minor Potential Hazard, Low plausibility
Applies to: Liver Disease, Renal Dysfunction
Systemically absorbed cromolyn is eliminated almost equally by renal and biliary routes. Although less than 1% of an orally ingested dose and approximately 8% of an orally inhaled dose is systemically available, the manufacturers recommend that a dosage reduction be considered in patients with impaired renal or hepatic function.
References
- "Product Information. Gastrocrom (cromolyn)." Rhone-Poulenc Rorer, Collegeville, PA.
- Fuller RW, Collier JG "The pharmacokinetic assessment of sodium cromoglycate." J Pharm Pharmacol 35 (1983): 289-92
- Rosenberg JL, Edlow D, Sneider R "Liver disease and vasculitis in a patient taking cromolyn." Arch Intern Med 138 (1978): 989-91
cromolyn drug Interactions
There is 1 drug interaction with cromolyn
Drug Interaction Classification
The classifications below are a general guideline only. It is difficult to determine the relevance of a particular drug interaction to any individual given the large number of variables.
| Major | Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. |
| Moderate | Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. |
| Minor | Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. |
Do not stop taking any medications without consulting your healthcare provider.
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