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Aminolevulinic acid topical Disease Interactions

There are 2 disease interactions with aminolevulinic acid topical:

Major

Aminolevulinic acid topical gel (Includes aminolevulinic acid topical) ↔ porphyria

Severe Potential Hazard, Moderate plausibility. Applies to: Porphyria

Photoactivation following topical application of aminolevulinic acid topical gel occurs when aminolevulinic acid (prodrug) is metabolized to protoporphyrin IX, a photoactive compound which accumulates in the skin. Therapy with aminolevulinic acid topical gel increases photosensitivity and it may cause uncontrolled phototoxic effects. Its use in contraindicated in patients with porphyria or photodermatoses.

Moderate

Aminolevulinic acid topical gel (Includes aminolevulinic acid topical) ↔ bleeding

Moderate Potential Hazard, Moderate plausibility. Applies to: Coagulation Defect

The use of aminolevulinic acid topical gel increases the risk of bleeding in patients with coagulation disorders. Care should be exercised during lesion preparation to avoid bleeding.

Aminolevulinic acid topical drug interactions

There are 169 drug interactions with aminolevulinic acid topical

Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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