Aminolevulinic acid topical Disease Interactions
There are 2 disease interactions with aminolevulinic acid topical:
Aminolevulinic acid topical gel (applies to aminolevulinic acid topical) porphyria
Major Potential Hazard, Moderate plausibility.
Photoactivation following topical application of aminolevulinic acid topical gel occurs when aminolevulinic acid (prodrug) is metabolized to protoporphyrin IX, a photoactive compound which accumulates in the skin. Therapy with aminolevulinic acid topical gel increases photosensitivity and it may cause uncontrolled phototoxic effects. Its use in contraindicated in patients with porphyria or photodermatoses.
Aminolevulinic acid topical gel (applies to aminolevulinic acid topical) bleeding
Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Coagulation Defect
The use of aminolevulinic acid topical gel increases the risk of bleeding in patients with coagulation disorders. Care should be exercised during lesion preparation to avoid bleeding.
Aminolevulinic acid topical drug interactions
There are 124 drug interactions with aminolevulinic acid topical
More about aminolevulinic acid topical
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- Drug class: topical photochemotherapeutics
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Drug Interaction Classification
|Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.|
|Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.|
|Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.|
|No interaction information available.|