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Ameluz (aminolevulinic acid topical) Disease Interactions

There are 2 disease interactions with Ameluz (aminolevulinic acid topical):


Aminolevulinic Acid Topical Gel (Includes Ameluz) ↔ Porphyria

Severe Potential Hazard, Moderate plausibility

Applies to: Porphyria

Photoactivation following topical application of aminolevulinic acid topical gel occurs when aminolevulinic acid (prodrug) is metabolized to protoporphyrin IX, a photoactive compound which accumulates in the skin. Therapy with aminolevulinic acid topical gel increases photosensitivity and it may cause uncontrolled phototoxic effects. Its use in contraindicated in patients with porphyria or photodermatoses.


Aminolevulinic Acid Topical Gel (Includes Ameluz) ↔ Bleeding

Moderate Potential Hazard, Moderate plausibility

Applies to: Coagulation Defect

The use of aminolevulinic acid topical gel increases the risk of bleeding in patients with coagulation disorders. Care should be exercised during lesion preparation to avoid bleeding.

Ameluz (aminolevulinic acid topical) drug Interactions

There are 165 drug interactions with Ameluz (aminolevulinic acid topical)

Drug Interaction Classification

The classifications below are a general guideline only. It is difficult to determine the relevance of a particular drug interaction to any individual given the large number of variables.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No information available.

Do not stop taking any medications without consulting your healthcare provider.

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