Zydelig Alternatives Compared
| Zydelig | Imbruvica | Venclexta |
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| Zydelig (idelalisib) | Imbruvica (ibrutinib) | Venclexta (venetoclax) |
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Prescription only
Zydelig is an oral PI3K inhibitor that may be used in combination with rituximab for the treatment of relapsed chronic lymphocytic leukemia. Severe and potentially life-threatening reactions have... View more |
Prescription only
Imbruvica is an oral tablet that may be taken once daily to treat certain types of cancers in adults or to treat chronic Graft Versus Host disease in adults and children older than 1 year. It works... View more |
Prescription only
Venclexta is a BCL-2 inhibitor that may be used to treat chronic lymphocytic leukemia (CLL), small cell lymphoma (SCL), or acute myeloid leukemia. It is an oral tablet that is administered once... View more |
Related suggestions Chronic Lymphocytic Leukemia
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| More about Zydelig (idelalisib) | More about Imbruvica (ibrutinib) | More about Venclexta (venetoclax) | ||||||||||||||||||||||||
| Generic Status | ||||||||||||||||||||||||||
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No lower-cost generic available |
No lower-cost generic available |
No lower-cost generic available |
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| Ratings & Reviews | ||||||||||||||||||||||||||
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Zydelig has an average rating of 4.5 out of 10 from a total of 2 ratings on Drugs.com. 50% of reviewers reported a positive effect, while 50% reported a negative effect. |
Imbruvica has an average rating of 5.9 out of 10 from a total of 53 ratings on Drugs.com. 53% of reviewers reported a positive effect, while 39% reported a negative effect. |
Venclexta has an average rating of 8.8 out of 10 from a total of 5 ratings on Drugs.com. 80% of reviewers reported a positive effect, while 0% reported a negative effect. |
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| Drug Class | ||||||||||||||||||||||||||
| Side Effects | ||||||||||||||||||||||||||
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Common side effects include:
See also: Zydelig side effects in more detail. |
Common side effects include:
See also: Imbruvica side effects in more detail. |
Common side effects include:
See also: Venclexta side effects in more detail. |
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| Pricing and Coupons * Prices are without insurance | ||||||||||||||||||||||||||
View all Zydelig prices |
View all Imbruvica prices |
View all Venclexta prices |
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| Dosage Form(s) Available | ||||||||||||||||||||||||||
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| Brand Names | ||||||||||||||||||||||||||
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N/A |
N/A |
N/A |
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| Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | ||||||||||||||||||||||||||
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8.2 hours |
6 hours |
26 hours |
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| CSA Schedule ** View glossary of terms | ||||||||||||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | ||||||||||||||||||||||||||
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Category D
Positive evidence of risk
See the full pregnancy warnings document. |
Category D
Positive evidence of risk
See the full pregnancy warnings document. |
Summary unavailable. See the full pregnancy warnings document. |
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| Drug Interactions | ||||||||||||||||||||||||||
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A total of 828 drugs are known to interact with Zydelig:
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A total of 440 drugs are known to interact with Imbruvica:
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A total of 399 drugs are known to interact with Venclexta:
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| Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||||||||||
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| Disease Interactions | ||||||||||||||||||||||||||
| First Approval Date | ||||||||||||||||||||||||||
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July 23, 2014 |
November 13, 2013 |
April 11, 2016 |
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| WADA Class View World Anti-Doping Agency classifications. | ||||||||||||||||||||||||||
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N/A |
N/A |
N/A |
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| More Information | ||||||||||||||||||||||||||
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| Related Treatment Guide | ||||||||||||||||||||||||||
** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.