Comparing Vicodin vs Cymbalta
Vicodin | Cymbalta |
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Vicodin (acetaminophen / hydrocodone) | Cymbalta (duloxetine) |
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Prescription only
Vicodin is a combination narcotic analgesic that may be used short-term for the relief of moderate-to-moderately severe pain that is unrelieved by nonopioid analgesics, and also for the relief of a... View more |
Prescription only
Cymbalta has antidepressant, anti-anxiety, and pain-relieving properties; however, it has been associated with a discontinuation syndrome on withdrawal even when tapered. Prescribed for Back Pain... View more |
Related suggestions Popular comparisons
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More about Vicodin (acetaminophen / hydrocodone) | More about Cymbalta (duloxetine) | ||||||||
Ratings & Reviews | |||||||||
Vicodin has an average rating of 7.7 out of 10 from a total of 146 ratings on Drugs.com. 71% of reviewers reported a positive effect, while 14% reported a negative effect. |
Cymbalta has an average rating of 6.3 out of 10 from a total of 1886 ratings on Drugs.com. 53% of reviewers reported a positive effect, while 30% reported a negative effect. |
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Drug Class | |||||||||
Side Effects | |||||||||
See also: Vicodin side effects in more detail. |
See also: Cymbalta side effects in more detail. |
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Generic Availability | |||||||||
N/A |
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Pricing and Coupons * Prices are without insurance | |||||||||
We could not find an exact match for this medicine. Try searching the Price Guide directly. |
View all Cymbalta prices |
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Dosage Forms Available | |||||||||
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Brand Names | |||||||||
Other acetaminophen / hydrocodone brands include: Xodol, Zyfrel | Other duloxetine brands include: Drizalma Sprinkle, Irenka | ||||||||
Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | |||||||||
3.8 hours |
17 hours |
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CSA Schedule ** View glossary of terms | |||||||||
High potential for abuse
Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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Pregnancy Category | |||||||||
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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Drug Interactions | |||||||||
A total of 645 drugs are known to interact with Vicodin:
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A total of 603 drugs are known to interact with Cymbalta:
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Alcohol/Food/Lifestyle Interactions | |||||||||
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Disease Interactions | |||||||||
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First Approval Date | |||||||||
January 07, 1983 |
N/A |
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WADA Class View World Anti-Doping Agency classifications. | |||||||||
N/A |
N/A |
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More Information | |||||||||
Patient resources | |||||||||
Professional Resources | |||||||||
Related Treatment Guide | |||||||||
** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.