Comparing Tizanidine vs Flexeril
Tizanidine | Flexeril |
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Tizanidine | Flexeril (cyclobenzaprine) |
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Prescription only
Tizanidine relieves muscle spasms but may cause sleepiness, a drop in blood pressure, and sedation. The dosage should be individualized and because it only lasts for a short time in the body, can be... View more |
Prescription only
Flexeril is a muscle relaxant that may be used short-term in addition to rest and physical therapy to treat muscle spasms caused by musculoskeletal conditions. Sedation is a common side effect... View more |
Related suggestions Muscle Spasm (Involuntary Hypertonicity)
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More about Tizanidine | More about Flexeril (cyclobenzaprine) | ||||||||
Ratings & Reviews | |||||||||
Tizanidine has an average rating of 6.1 out of 10 from a total of 377 ratings on Drugs.com. 48% of reviewers reported a positive effect, while 30% reported a negative effect. |
Flexeril has an average rating of 6.0 out of 10 from a total of 237 ratings on Drugs.com. 47% of reviewers reported a positive effect, while 28% reported a negative effect. |
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Drug Class | |||||||||
Side Effects | |||||||||
See also: tizanidine side effects in more detail. |
See also: Flexeril side effects in more detail. |
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Generic Availability | |||||||||
Lower cost generic |
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Pricing and Coupons * Prices are without insurance | |||||||||
View all tizanidine prices |
We could not find an exact match for this medicine. Try searching the Price Guide directly. |
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Dosage Form(s) Available | |||||||||
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N/A |
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Brand Names | |||||||||
Zanaflex | Other cyclobenzaprine brands include: Amrix, Comfort Pac with Cyclobenzaprine | ||||||||
Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | |||||||||
2.5 hours |
72 hours |
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CSA Schedule ** View glossary of terms | |||||||||
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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Pregnancy Category | |||||||||
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category B
No proven risk in humans
See the full pregnancy warnings document. |
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Drug Interactions | |||||||||
A total of 608 drugs are known to interact with tizanidine:
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A total of 440 drugs are known to interact with Flexeril:
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Alcohol/Food/Lifestyle Interactions | |||||||||
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Disease Interactions | |||||||||
First Approval Date | |||||||||
November 27, 1996 |
August 26, 1977 |
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WADA Class View World Anti-Doping Agency classifications. | |||||||||
N/A |
N/A |
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More Information | |||||||||
Patient resources | |||||||||
Professional Resources | |||||||||
Related Treatment Guide | |||||||||
** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.