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Comparing Pyrimethamine vs Sulfadiazine

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Pyrimethamine Remove Pyrimethamine from your drug comparison Sulfadiazine Remove Sulfadiazine from your drug comparison
View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Pyrimethamine Remove Pyrimethamine from your drug comparison Sulfadiazine Remove Sulfadiazine from your drug comparison

Prescribed for Malaria Prevention, Toxoplasmosis, Toxoplasmosis - Prophylaxis, Pneumocystis Pneumonia Prophylaxis. pyrimethamine may also be used for purposes not listed in this medication guide.

Prescribed for Rheumatic Fever Prophylaxis, Toxoplasmosis, Toxoplasmosis - Prophylaxis. sulfadiazine may also be used for purposes not listed in this medication guide.

Prescription only

Prescription only

Ratings & Reviews

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10.0
1 Reviews

N/A
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Drug Class

Side Effects

See the full pyrimethamine side effects document.

See the full sulfadiazine side effects document.

Pricing and Coupons

* Prices are without insurance
Quantity 30 tablet
Dosage 25 mg
Per Unit* $558.13
Cost* $16,743.88

View all pyrimethamine prices

Quantity 100 tablet
Dosage 500 mg
Per Unit* $3.63
Cost* $362.82

View all sulfadiazine prices

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Get free Discount Card

Generic Availability

Yes (this medicine)

Yes (this medicine)

Dosage Form(s) Available
  • Oral tablet
  • Oral tablet

Brand Names
Daraprim

N/A

Half Life

The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value.

123 hours

10 hours

CSA Schedule**

View glossary of terms.
N
Not a controlled drug

Is not subject to the Controlled Substances Act.
N
Not a controlled drug

Is not subject to the Controlled Substances Act.

Pregnancy Category
C
Category C Risk cannot be ruled out

See the full Pregnancy Warnings document.
C
Category C Risk cannot be ruled out

See the full Pregnancy Warnings document.

FDA Alerts

N/A

N/A

Drug Interactions

A total of 27 drugs are known to interact with pyrimethamine:

  • 4 major drug interactions (9 brand and generic names)
  • 21 moderate drug interactions (131 brand and generic names)
  • 2 minor drug interactions (8 brand and generic names)

A total of 101 drugs are known to interact with sulfadiazine:

  • 16 major drug interactions (44 brand and generic names)
  • 84 moderate drug interactions (364 brand and generic names)
  • 1 minor drug interactions (2 brand and generic names)

Alcohol/Food/Lifestyle Interactions

No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider.

No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider.

Disease Interactions

First Approval Date

January 23, 1953

August 11, 1941

WADA Class

View World Anti-Doping Agency classifications.

N/A

N/A

More Information

Consumer Resources

Professional Resources

Related Treatment Guide

** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

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