Comparing Pyrimethamine vs Sulfadiazine
| Pyrimethamine Remove Pyrimethamine from your drug comparison | Sulfadiazine Remove Sulfadiazine from your drug comparison |
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| Pyrimethamine Remove Pyrimethamine from your drug comparison | Sulfadiazine Remove Sulfadiazine from your drug comparison |
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Prescribed for Malaria Prevention, Toxoplasmosis, Toxoplasmosis - Prophylaxis, Pneumocystis Pneumonia Prophylaxis. pyrimethamine may also be used for purposes not listed in this medication guide. |
Prescribed for Toxoplasmosis, Rheumatic Fever Prophylaxis, Toxoplasmosis - Prophylaxis. sulfadiazine may also be used for purposes not listed in this medication guide. |
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Prescription only |
Prescription only |
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Ratings & Reviews |
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Drug Class |
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Side Effects |
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See the full pyrimethamine side effects document. |
See the full sulfadiazine side effects document. |
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Pricing and Coupons* Prices are without insurance |
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View all pyrimethamine prices |
View all sulfadiazine prices |
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Generic Availability |
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Yes (this medicine) |
Yes (this medicine) |
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Dosage Form(s) Available |
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Brand Names |
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| Daraprim |
N/A |
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Half LifeThe half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. |
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123 hours |
10 hours |
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CSA Schedule**View glossary of terms. |
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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Pregnancy Category |
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Category C
Risk cannot be ruled out
See the full Pregnancy Warnings document. |
Category C
Risk cannot be ruled out
See the full Pregnancy Warnings document. |
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Drug Interactions |
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A total of 28 drugs are known to interact with pyrimethamine:
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A total of 109 drugs are known to interact with sulfadiazine:
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Alcohol/Food/Lifestyle Interactions |
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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Disease Interactions |
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First Approval Date |
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January 23, 1953 |
August 11, 1941 |
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WADA ClassView World Anti-Doping Agency classifications. |
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N/A |
N/A |
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More Information |
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Patient resources |
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Professional Resources |
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Related Treatment Guide |
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** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.