Sulfadiazine Drug Interactions
A total of 120 drugs (645 brand and generic names) are known to interact with sulfadiazine.
- 24 major drug interactions (122 brand and generic names)
- 93 moderate drug interactions (516 brand and generic names)
- 3 minor drug interactions (7 brand and generic names)
Check for interactions with sulfadiazine
Common medications checked in combination with sulfadiazine
- Acetylsalicylic Acid (aspirin)
- Benadryl (diphenhydramine)
- Daraprim (pyrimethamine)
- Depakote (divalproex sodium)
- Diflucan (fluconazole)
- Fioricet (acetaminophen / butalbital / caffeine)
- Mucinex DM (dextromethorphan / guaifenesin)
- Nasonex (mometasone nasal)
- Neupogen (filgrastim)
- Paracetamol (acetaminophen)
- Robaxin-750 (methocarbamol)
- Stribild (cobicistat / elvitegravir / emtricitabine / tenofovir)
- Vitamin B1 (thiamine)
- Vitamin B12 (cyanocobalamin)
- Vitamin C (ascorbic acid)
- Vitamin D3 (cholecalciferol)
- Vitamin K (phytonadione)
- Vitamin K1 (phytonadione)
- Zofran (ondansetron)
- Zoloft (sertraline)
sulfadiazine disease Interactions
There are 9 disease interactions with sulfadiazine which include:
- Hematologic Toxicity
- Hypersensitivity Reactions
- Liver Disease
- Porphyria
- Renal Dysfunction
- Colitis
- Crystalluria
- Hemodialysis
- Urinary Obstruction
Drug Interaction Classification
The classifications below are a general guideline only. It is difficult to determine the relevance of a particular drug interaction to any individual given the large number of variables.
| Major | Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. |
| Moderate | Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. |
| Minor | Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. |
Do not stop taking any medications without consulting your healthcare provider.
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