Comparing Naltrexone vs Buprenorphine
Naltrexone | Buprenorphine |
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Naltrexone | Buprenorphine |
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Prescription only
Naltrexone is used as an adjunct to social and psychotherapy in the treatment of opioid and alcohol addiction. People taking naltrexone need to have completely stopped taking all types of opioids... View more |
Prescription only
Buprenorphine is a potent analgesic that should be only used to treat moderate to severe pain or for the treatment of opioid addiction under strict conditions. Different formulations of the drug... View more |
Related suggestions |
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More about Naltrexone | More about Buprenorphine | ||||||||||||||||
Ratings & Reviews | |||||||||||||||||
Naltrexone has an average rating of 8.0 out of 10 from a total of 591 ratings on Drugs.com. 76% of reviewers reported a positive effect, while 15% reported a negative effect. |
Buprenorphine has an average rating of 6.7 out of 10 from a total of 1118 ratings on Drugs.com. 58% of reviewers reported a positive effect, while 26% reported a negative effect. |
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Drug Class | |||||||||||||||||
Side Effects | |||||||||||||||||
See also: naltrexone side effects in more detail. |
See also: buprenorphine side effects in more detail. |
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Generic Availability | |||||||||||||||||
Lower cost generic |
Lower cost generic |
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Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all naltrexone prices |
View all buprenorphine prices |
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Dosage Form(s) Available | |||||||||||||||||
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Brand Names | |||||||||||||||||
Vivitrol | Belbuca, Brixadi, Buprenex, Butrans, Sublocade | ||||||||||||||||
Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | |||||||||||||||||
10 hours |
48 hours |
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CSA Schedule ** View glossary of terms | |||||||||||||||||
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Moderate abuse potential
Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence. |
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Pregnancy Category | |||||||||||||||||
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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Drug Interactions | |||||||||||||||||
A total of 338 drugs are known to interact with naltrexone:
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A total of 684 drugs are known to interact with buprenorphine:
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Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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Disease Interactions | |||||||||||||||||
First Approval Date | |||||||||||||||||
November 20, 1984 |
December 29, 1981 |
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WADA Class View World Anti-Doping Agency classifications. | |||||||||||||||||
N/A |
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More Information | |||||||||||||||||
Patient resources | |||||||||||||||||
Professional Resources | |||||||||||||||||
Related Treatment Guide | |||||||||||||||||
** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.