Comparing Naloxone vs Vivitrol
| Naloxone | Vivitrol (naltrexone) |
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| Naloxone | Vivitrol (naltrexone) |
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Prescription and OTC
Naloxone can be used by consumers and the lay-public, first-responders and healthcare providers to help reverse an overdose due to opioids (narcotics), including heroin and prescription opioids. It... View more |
Prescription only
Vivitrol is used for the treatment of alcohol or opioid addiction alongside social therapy and psychotherapy. It is administered by intramuscular injection by a health professional once every four... View more |
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| More about Naloxone | More about Vivitrol (naltrexone) | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Naloxone has an average rating of 7.7 out of 10 from a total of 27 ratings on Drugs.com. 70% of reviewers reported a positive effect, while 22% reported a negative effect. |
Vivitrol has an average rating of 7.5 out of 10 from a total of 203 ratings on Drugs.com. 67% of reviewers reported a positive effect, while 20% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
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View all Naloxone side effects |
View all Vivitrol side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
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Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Naloxone prices |
View all Vivitrol prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Kloxxado, Narcan, Rextovy, Rezenopy, RiVive, Zimhi |
N/A |
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| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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3 hours |
10 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 30 drugs are known to interact with Naloxone:
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A total of 352 drugs are known to interact with Vivitrol:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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April 13, 1971 |
April 13, 2006 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
| Patient Resources | |||||||||||||||||
| Professional Resources | |||||||||||||||||
| Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.