Naloxone use while Breastfeeding
Drugs containing Naloxone: Suboxone, Zubsolv, Evzio, Narcan Nasal Spray, Narcan Injection, Bunavail, Talwin Nx, Targiniq ER, Cassipa
Medically reviewed by Drugs.com. Last updated on Apr 3, 2019.
Naloxone Levels and Effects while Breastfeeding
Summary of Use during Lactation
No information is available on the excretion of naloxone into breastmilk. Because it is not orally bioavailable, it is unlikely to affect the breastfed infant. However, if naloxone is required by the mother for an opiate overdose, she should withhold nursing until the opiate is out of her system.
Drug Levels
Maternal Levels. Relevant published information was not found as of the revision date.
Infant Levels. Relevant published information was not found as of the revision date.
Effects in Breastfed Infants
Relevant published information was not found as of the revision date.
Effects on Lactation and Breastmilk
In contrast to its effect in some animal species, naloxone does not affect suckling-induced secretion of oxytocin or prolactin in postpartum women.[1][2]
Alternate Drugs to Consider
References
1. Cholst IN, Wardlaw SL, Newman CB, Frantz AG. Prolactin response to breast stimulation in lactating women is not mediated by endogenous opioids. Am J Obstet Gynecol. 1984;150:558-61. PMID: 6496587
2. Johnson MR, Andrews MA, Seckl JR, Lightman SL. Effect of naloxone on neurohypophyseal peptide responses to breast feeding and breast stimulation in man. Clin Endocrinol (Oxf). 1990;33:81-6. PMID: 2401100
Naloxone Identification
Substance Name
Naloxone
CAS Registry Number
465-65-6
Drug Class
Breast Feeding
Lactation
Narcotic Antagonists
Administrative Information
LactMed Record Number
778
Disclaimer
Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
More about naloxone
- Side Effects
- During Pregnancy
- Dosage Information
- Drug Interactions
- Compare Alternatives
- Support Group
- Pricing & Coupons
- 17 Reviews
- Drug class: antidotes
- FDA Alerts (1)
Consumer resources
- Naloxone nasal
- Naloxone Auto-Injection
- Naloxone Injection
- Naloxone Nasal Spray
- Naloxone Injection (Advanced Reading)
- Naloxone Nasal (Advanced Reading)
Other brands: Evzio, Narcan Nasal Spray, Narcan Injection
