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Naloxone Interactions

There are 30 drugs known to interact with naloxone, along with 4 disease interactions. Of the total drug interactions, 1 is major, 27 are moderate, and 2 are minor.

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Medications known to interact with naloxone

Note: Showing generic names only.

Naloxone disease interactions

There are 4 disease interactions with naloxone which include:


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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.