Comparing Cuprimine vs Syprine
| Cuprimine (penicillamine) | Syprine (trientine) |
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| Cuprimine (penicillamine) | Syprine (trientine) |
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Prescription only
Prescribed for Wilson's Disease, Cystinuria, Rheumatoid Arthritis. Cuprimine may also be used for purposes not listed in this medication guide. |
Prescription only
Prescribed for Wilson's Disease. Syprine may also be used for purposes not listed in this medication guide. |
Related suggestions Wilson's Disease
Popular comparisons
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| More about Cuprimine (penicillamine) | More about Syprine (trientine) | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Cuprimine has an average rating of 10.0 out of 10 from a total of 1 ratings on Drugs.com. 100% of reviewers reported a positive effect, while 0% reported a negative effect. |
Syprine has an average rating of 10.0 out of 10 from a total of 1 ratings on Drugs.com. 100% of reviewers reported a positive effect, while 0% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
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View all Cuprimine side effects |
View all Syprine side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Cuprimine prices |
View all Syprine prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Other penicillamine brands include: D-Penamine, Depen, Depen Titratabs | Other trientine brands include: Clovique, Cuvrior | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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3.2 hours |
N/A |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category D
Positive evidence of risk
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 123 drugs are known to interact with Cuprimine:
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A total of 46 drugs are known to interact with Syprine:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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December 04, 1970 |
November 08, 1985 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
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| Professional Resources | |||||||||||||||||
| Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.