Syprine Side Effects

Generic Name: trientine

Note: This document contains side effect information about trientine. Some of the dosage forms listed on this page may not apply to the brand name Syprine.

For the Consumer

Applies to trientine: oral capsule

Along with its needed effects, trientine (the active ingredient contained in Syprine) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor as soon as possible if any of the following side effects occur while taking trientine:

• Unusually pale skin
• unusual tiredness

• Fever
• general feeling of discomfort, illness, or weakness
• joint pain
• skin rash, blisters, hives, or itching
• swollen glands

Note: Signs of anemia are more likely to occur in children, menstruating women, and pregnant women, who usually need more iron than other patients. If these signs appear during trientine treatment, your doctor will need to do some tests.

For Healthcare Professionals

Applies to trientine: oral capsule

Nervous system

Frequency not reported: Myasthenia gravis^[Ref]

Gastrointestinal

Frequency not reported: Nausea, duodenitis, severe colitis, heartburn, epigastric pain and tenderness, acute gastritis, aphthoid ulcers, abdominal pain, melena^[Ref]

Hematologic

Very rare (less than 0.01%): Anemia, hypochromic microcytic anemia^[Ref]

Musculoskeletal

Frequency not reported: Systemic lupus erythematosus, dystonia, muscular spasm, cramps, muscle pain, rhabdomyolysis^[Ref]

Metabolic

Frequency not reported: Iron deficiency, anorexia^[Ref]

Dermatologic

Frequency not reported: Skin rash, thickening/fissuring/flaking of the skin^[Ref]

Other

Frequency not reported: Malaise, weakness^[Ref]

Some side effects of Syprine may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. Drugs.com does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.