Syprine Side Effects

Generic Name: trientine

Note: This document contains side effect information about trientine. Some of the dosage forms listed on this page may not apply to the brand name Syprine.

For the Consumer

Applies to trientine: oral capsule

Along with its needed effects, trientine (the active ingredient contained in Syprine) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor as soon as possible if any of the following side effects occur while taking trientine:

More Common

• Unusually pale skin
• unusual tiredness

Rare

• Fever
• general feeling of discomfort, illness, or weakness
• joint pain
• skin rash, blisters, hives, or itching
• swollen glands

Note: Signs of anemia are more likely to occur in children, menstruating women, and pregnant women, who usually need more iron than other patients. If these signs appear during trientine treatment, your doctor will need to do some tests.

For Healthcare Professionals

Applies to trientine: oral capsule

Nervous system

Frequency not reported: Myasthenia gravis^[Ref]

Gastrointestinal

Frequency not reported: Nausea, duodenitis, severe colitis, heartburn, epigastric pain and tenderness, acute gastritis, aphthoid ulcers, abdominal pain, melena^[Ref]

Hematologic

Very rare (less than 0.01%): Anemia, hypochromic microcytic anemia^[Ref]

Musculoskeletal

Frequency not reported: Systemic lupus erythematosus, dystonia, muscular spasm, cramps, muscle pain, rhabdomyolysis^[Ref]

Metabolic

Frequency not reported: Iron deficiency, anorexia^[Ref]

Dermatologic

Frequency not reported: Skin rash, thickening/fissuring/flaking of the skin^[Ref]

Other

Frequency not reported: Malaise, weakness^[Ref]

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.

Medical Disclaimer