Syprine Side Effects
Generic name: trientine
Medically reviewed by Drugs.com. Last updated on Feb 27, 2022.
Note: This document contains side effect information about trientine. Some of the dosage forms listed on this page may not apply to the brand name Syprine.
For the Consumer
Applies to trientine: oral capsule
Side effects requiring immediate medical attention
Along with its needed effects, trientine (the active ingredient contained in Syprine) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor as soon as possible if any of the following side effects occur while taking trientine:
More common
- Symptoms of anemia- Unusually pale skin
- unusual tiredness
Rare
- Fever
- general feeling of discomfort, illness, or weakness
- joint pain
- skin rash, blisters, hives, or itching
- swollen glands
Note: Signs of anemia are more likely to occur in children, menstruating women, and pregnant women, who usually need more iron than other patients. If these signs appear during trientine treatment, your doctor will need to do some tests.
For Healthcare Professionals
Applies to trientine: oral capsule
Nervous system
Frequency not reported: Myasthenia gravis[Ref]
Gastrointestinal
Frequency not reported: Nausea, duodenitis, severe colitis, heartburn, epigastric pain and tenderness, acute gastritis, aphthoid ulcers, abdominal pain, melena[Ref]
Hematologic
Very rare (less than 0.01%): Anemia, hypochromic microcytic anemia[Ref]
Musculoskeletal
Frequency not reported: Systemic lupus erythematosus, dystonia, muscular spasm, cramps, muscle pain, rhabdomyolysis[Ref]
Metabolic
Frequency not reported: Iron deficiency, anorexia[Ref]
Dermatologic
Frequency not reported: Skin rash, thickening/fissuring/flaking of the skin[Ref]
Other
Frequency not reported: Malaise, weakness[Ref]
More about Syprine (trientine)
- Drug interactions
- Dosage information
- During pregnancy or Breastfeeding
- Drug images
- Compare alternatives
- Pricing & coupons
- Generic availability
- En español
- Drug class: chelating agents
Patient resources
- Other brands
- Clovique
Professional resources
Related treatment guides
References
1. "Product Information. Syprine (trientine)." Aton Pharma, Lawrenceville, NJ.
2. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Some side effects may not be reported. You may report them to the FDA.
