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Syprine Alternatives Compared

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Syprine Remove Syprine from your drug comparison Penicillamine Remove Penicillamine from your drug comparison Cuprimine Remove Cuprimine from your drug comparison
View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Syprine trientine Remove Syprine from your drug comparison Penicillamine Remove Penicillamine from your drug comparison Cuprimine penicillamine Remove Cuprimine from your drug comparison

Prescribed for Wilson's Disease. Syprine may also be used for purposes not listed in this medication guide.

Prescribed for Cystinuria, Wilson's Disease, Rheumatoid Arthritis. penicillamine may also be used for purposes not listed in this medication guide.

Prescribed for Cystinuria, Wilson's Disease, Rheumatoid Arthritis. Cuprimine may also be used for purposes not listed in this medication guide.

Prescription only

Prescription only

Prescription only

Ratings & Reviews

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View all 1 reviews

Drug Class

Side Effects

See the full Syprine side effects document.

Commonly reported side effects include: cheilosis, epigastric pain, glossitis, oral mucosa ulcer, ageusia, dysgeusia.

See the full penicillamine side effects document.

Common side effects include: cheilosis, epigastric pain, glossitis, oral mucosa ulcer, ageusia, dysgeusia.

See the full Cuprimine side effects document.

Pricing and Coupons

* Prices are without insurance
Quantity 100 capsule
Dosage 250 mg
Per Unit* $222.12
Cost* $22,212.04

View all Syprine prices and generic prices

Quantity 100 capsule
Dosage 250 mg
Per Unit* $176.08 - $209.08
Cost* $17,608.26 - $20,908.04

View all penicillamine prices

Quantity 100 capsule
Dosage 250 mg
Per Unit* $273.50
Cost* $27,350.44

View all Cuprimine prices and generic prices

Get free Discount Card

Get free Discount Card

Get free Discount Card

Generic Availability

Yes

Yes (this medicine)

Yes

Dosage Form(s) Available
  • Oral capsule
  • Oral capsule
  • Oral tablet
  • Oral capsule

Brand Names
Other trientine brands include: Clovique Cuprimine, D-Penamine, Depen, Depen Titratabs Other penicillamine brands include: D-Penamine, Depen, Depen Titratabs

Half Life

The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value.

N/A

3.2 hours

3.2 hours

CSA Schedule**

View glossary of terms.
N
Not a controlled drug

Is not subject to the Controlled Substances Act.
N
Not a controlled drug

Is not subject to the Controlled Substances Act.
N
Not a controlled drug

Is not subject to the Controlled Substances Act.

Pregnancy Category
C
Category C Risk cannot be ruled out

See the full Pregnancy Warnings document.
D
Category D Positive evidence of risk

See the full Pregnancy Warnings document.
D
Category D Positive evidence of risk

See the full Pregnancy Warnings document.

FDA Alerts

N/A

N/A

N/A

Drug Interactions

A total of 37 drugs are known to interact with Syprine:

  • 34 moderate drug interactions (1358 brand and generic names)
  • 3 minor drug interactions (15 brand and generic names)

A total of 89 drugs are known to interact with penicillamine:

  • 21 major drug interactions (106 brand and generic names)
  • 68 moderate drug interactions (1470 brand and generic names)

A total of 89 drugs are known to interact with Cuprimine:

  • 21 major drug interactions (106 brand and generic names)
  • 68 moderate drug interactions (1470 brand and generic names)

Alcohol/Food/Lifestyle Interactions
  • Take trientine on an empty stomach 1 hour before or 2 hours after a meal and at least one hour... View more
  • You may experience reduced absorption of penicillAMINE in the presence of food. The effectiveness... View more
  • You may experience reduced absorption of penicillAMINE in the presence of food. The effectiveness... View more

Disease Interactions

First Approval Date

November 08, 1985

December 04, 1970

December 04, 1970

WADA Class

View World Anti-Doping Agency classifications.

N/A

N/A

N/A

More Information

Consumer Resources

Professional Resources

Related Treatment Guide

** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

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