Comparing Combigan vs Simbrinza
| Combigan (brimonidine / timolol) | Simbrinza (brimonidine / brinzolamide) |
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| Combigan (brimonidine / timolol) | Simbrinza (brimonidine / brinzolamide) |
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Prescription only
Prescribed for Glaucoma, Glaucoma/Intraocular Hypertension, Intraocular Hypertension. Combigan may also be used for purposes not listed in this medication guide. |
Prescription only
Prescribed for Glaucoma - Open Angle, Intraocular Hypertension. Simbrinza may also be used for purposes not listed in this medication guide. |
Related suggestions Intraocular Hypertension
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| More about Combigan (brimonidine / timolol) | More about Simbrinza (brimonidine / brinzolamide) | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Combigan has an average rating of 4.9 out of 10 from a total of 25 ratings on Drugs.com. 40% of reviewers reported a positive effect, while 48% reported a negative effect. |
Simbrinza has an average rating of 5.2 out of 10 from a total of 28 ratings on Drugs.com. 29% of reviewers reported a positive effect, while 29% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
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View all Combigan side effects |
View all Simbrinza side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Combigan prices |
View all Simbrinza prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
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N/A |
N/A |
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| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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7 hours |
2664 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 548 drugs are known to interact with Combigan:
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A total of 378 drugs are known to interact with Simbrinza:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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October 30, 2007 |
N/A |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
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| More Information | |||||||||||||||||
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| Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.