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Combigan Side Effects

Generic name: brimonidine / timolol ophthalmic

Medically reviewed by Drugs.com. Last updated on Aug 23, 2024.

Note: This document provides detailed information about Combigan Side Effects associated with brimonidine / timolol ophthalmic. Some dosage forms listed on this page may not apply specifically to the brand name Combigan.

Applies to brimonidine/timolol ophthalmic: ophthalmic solution.

Serious side effects of Combigan

Along with its needed effects, brimonidine/timolol ophthalmic may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking brimonidine / timolol ophthalmic:

More common

  • burning, dry, or itching eyes
  • discharge or excessive tearing
  • redness, pain, swelling of the eye, eyelid, or inner lining of the eyelid
  • stinging in the eyes
  • tiny bumps on lining of the eyelid

Less common

  • blurred or loss of vision
  • disturbed color perception
  • dizziness
  • double vision
  • feeling of having something in the eye
  • halos around lights
  • headache
  • nervousness
  • night blindness
  • pounding in the ears
  • sensitivity of the eyes to light
  • slow, fast, or irregular heartbeat
  • tunnel vision
  • watery eyes

Get emergency help immediately if any of the following symptoms of overdose occur while taking brimonidine / timolol ophthalmic:

Symptoms of overdose

Other side effects of Combigan

Some side effects of brimonidine / timolol ophthalmic may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

  • dry mouth
  • feeling sad or empty
  • irritability
  • lack of appetite
  • lack or loss of strength
  • loss of interest or pleasure
  • sleepiness or unusual drowsiness
  • trouble concentrating
  • trouble sleeping

For healthcare professionals

Applies to brimonidine / timolol ophthalmic: ophthalmic solution.

General

The commonly reported side effects were allergic conjunctivitis, conjunctival folliculosis, conjunctival hyperemia, eye pruritus, ocular burning, and stinging.[Ref]

Cardiovascular

Brimonidine:

Timolol:

Gastrointestinal

Brimonidine:

Timolol:

Immunologic

Brimonidine:

Timolol:

Nervous system

Timolol:

Psychiatric

Brimonidine:

Timolol:

Respiratory

Brimonidine:

Timolol:

Genitourinary

Timolol:

Ocular

Brimonidine:

Timolol:

Musculoskeletal

Timolol:

Other

Timolol:

Dermatologic

Brimonidine:

Timolol:

Hepatic

Metabolic

Brimonidine:

Timolol:

References

1. Cerner Multum, Inc. "UK Summary of Product Characteristics."

2. (2007) "Product Information. Combigan (brimonidine-timolol ophthalmic)." Allergan Inc

3. Cerner Multum, Inc. "Australian Product Information."

Further information

Combigan side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.