Comparing Bevacizumab vs Zejula

For Glioblastoma Multiforme: I had stage 4 gliosarcoma in March and wasn't supposed to make it very long. After surgery, aggressive radiation and 3 rounds of 400mg Temidar (pardon the spelling), my first MRI showed the tumor was growing back. My oncologist put me on bi-monthly drips of Avastin to go with the Temidar. My second MRI showed a 30% decrease in the size of my tumor. My legs are weak, but I'll take it!! Thank God for Avastin and the oncologist. I am the first person I know of that was given Avastin for Gliosarcoma.

For Ovarian Cancer: I've been on the 200mg dose for just under 3 months. While my labs are ok, I have unbelievable fatigue. It seems like no amount of rest helps. Not very conducive to working even part time. I come home & lay on the bed or couch with no motivation. We'll see what the doc says at the 3 month visit. But this is my 3rd recurrence & yet i don't want to keep taking this drug

For Ovarian Cancer: I've been on Zejula now for 3 months. Side effects are getting slightly better. 300mg at bedtime due to persistent nausea prior to starting this drug. I take it and feel so tired that you would think I would sleep but I lay down and my mind won't turn off. Usually drop off at 1am then wake at 430am. Sometimes, I can get back to sleep. Really bad fatigue and joint pain. H&H are slowly dropping but not critical. I do like the fact that my white count while low does not need Nupagen. I have trouble concentrating and focusing on things. Motivation is a thing of the past. Ca125 is climbing since I started the drug. I see oncologist tomorrow for 3 month check-in. .