Comparing Afinitor vs Methotrexate
Afinitor | Methotrexate |
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Afinitor (everolimus) | Methotrexate |
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Prescription only
Afinitor (everolimus) is a targeted medicine that may be used to treat various cancers and TSC-associated conditions. It reduces the blood supply to the cancers which slows down their growth and... View more |
Prescription only
Methotrexate may be considered for the treatment of psoriasis or rheumatoid arthritis if other treatments have failed. It may also be used in certain cancers. Side effects can be severe and... View more |
Related suggestions Pancreatic Cancer
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More about Afinitor (everolimus) | More about Methotrexate | ||||||||||||||||
Ratings & Reviews | |||||||||||||||||
Afinitor has an average rating of 5.4 out of 10 from a total of 20 ratings on Drugs.com. 47% of reviewers reported a positive effect, while 42% reported a negative effect. |
Methotrexate has an average rating of 6.6 out of 10 from a total of 334 ratings on Drugs.com. 54% of reviewers reported a positive effect, while 23% reported a negative effect. |
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Drug Class | |||||||||||||||||
Side Effects | |||||||||||||||||
See also: Afinitor side effects in more detail. |
See also: methotrexate side effects in more detail. |
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Generic Availability | |||||||||||||||||
Lower cost generic |
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Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Afinitor prices |
View all methotrexate prices |
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Dosage Forms Available | |||||||||||||||||
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Brand Names | |||||||||||||||||
Other everolimus brands include: Afinitor Disperz, Torpenz, Zortress | Jylamvo, Methotrexate LPF Sodium, Otrexup, Rasuvo, Trexall, Xatmep | ||||||||||||||||
Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | |||||||||||||||||
35 hours |
15 hours |
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CSA Schedule ** View glossary of terms | |||||||||||||||||
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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Pregnancy Category | |||||||||||||||||
Category D
Positive evidence of risk
See the full pregnancy warnings document. |
Category X
Not for use in pregnancy
See the full pregnancy warnings document. |
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Drug Interactions | |||||||||||||||||
A total of 513 drugs are known to interact with Afinitor:
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A total of 694 drugs are known to interact with methotrexate:
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Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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Disease Interactions | |||||||||||||||||
First Approval Date | |||||||||||||||||
March 30, 2009 |
December 07, 1953 |
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WADA Class View World Anti-Doping Agency classifications. | |||||||||||||||||
N/A |
N/A |
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More Information | |||||||||||||||||
Patient resources | |||||||||||||||||
Professional Resources | |||||||||||||||||
Related Treatment Guide | |||||||||||||||||
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** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.