Comparing Afinitor vs Votrient
Afinitor Remove Afinitor from your drug comparison | Votrient Remove Votrient from your drug comparison |
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Afinitor everolimus Remove Afinitor from your drug comparison | Votrient pazopanib Remove Votrient from your drug comparison | ||||||||||||||||
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Afinitor (everolimus) is a targeted medicine that may be used to treat various cancers and TSC-associated conditions. It reduces the blood supply to the cancers which slows down their growth and... View more |
Prescribed for Soft Tissue Sarcoma, Renal Cell Carcinoma. Votrient may also be used for purposes not listed in this medication guide. |
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Prescription only |
Prescription only |
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Ratings & ReviewsRecent helpful reviews |
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5.6
For Breast Cancer: Although the medication did effectively treat my cancer the side effects were so severe that I decided to discontinue use of the drug and try an alternate treatment. Skin rash started on my hands initially and spread to my entire body causing severe itching and scratching which led to something looking like opened bug bites all over. Severe gum irritation described by my dental hygienist as your gums are flapping in the wind, also red swollen gums which caused me to be unable to eat anything not soft. Lost 10 lbs the first two months. Also projectile vomiting, diahrea and nausea. At three months I found it had made me diabetic and raised my triglycerides to over 500. That's when I opted to stop treatment. |
8.2
For Renal Cell Carcinoma: I have been on Votrient since Jan 2010. Started with a right kidney in 1999. In 2009 my family doctor suggested that I have a pulmonary doctor run some CTs to see what he thought. After 8 months of CTs, I had to go and get a biopsy and it proved 2 clear and 2 renal cell carcinoma had appeared between my lungs. I checked a couple of oncologists in town. Been on the medicine since January 2010 and have little significant change. A little diarrhea once in a while and headaches, some dizziness on occasion but no significant change. Feel real good about the treatment. Would recommend it to anyone. For Renal Cell Carcinoma: RCC detected May 2018. Left kidney removed 20 yrs ago, started Votrient 800 mg on June 1, 2018. First follow up PET scan will be August 30th, to see how it is doing. Most side effects, diarrhea most days, hair turning white, bruising easily, now feet are very tender, even thou I am following instructions on applying urea lotion on both feet and hands twice daily. Take the Votrient first thing out of bed in the AM, with hopes I flush out early enough to have an active life, although I am limited some days, but must always know where restrooms are. When I started the Votrient, I went directly to 800mg, and have stayed on it daily since, I feel that I must tough it out, and stay with it, to give it the best chance to work. Praying for good scan results. God Bless you folks that are in the same fight, stay on meds, stay as active as you can (I walk 20-30 minutes every day), and eat to keep weight up which will help with your strength. My prayers are with you. |
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Drug Class |
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Side Effects |
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Common side effects include: infection, decreased hemoglobin, increased serum glucose, lymphocytopenia, and stomatitis. See the full Afinitor side effects document. |
Common side effects include: bleeding tendency disorder, abdominal pain, decreased serum glucose, decreased serum magnesium, decreased serum phosphate, diarrhea, fatigue, hypertension, increased serum alanine aminotransferase, increased serum aspartate aminotransferase, increased serum bilirubin, leukopenia, nausea, neutropenia, thrombocytopenia, vomiting, and anorexia. See the full Votrient side effects document. |
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Pricing and Coupons* Prices are without insurance |
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View all Afinitor prices and generic prices |
View all Votrient prices |
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Generic Availability |
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No |
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Dosage Form(s) Available |
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Brand Names |
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Other everolimus brands include: Afinitor Disperz, Zortress |
N/A |
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Half LifeThe half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. |
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35 hours |
30.9 hours |
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CSA Schedule**View glossary of terms. |
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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Pregnancy Category |
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Category D
Positive evidence of risk
See the full Pregnancy Warnings document. |
Category D
Positive evidence of risk
See the full Pregnancy Warnings document. |
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FDA Alerts |
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N/A |
N/A |
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Drug Interactions |
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A total of 415 drugs are known to interact with Afinitor:
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A total of 542 drugs are known to interact with Votrient:
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Alcohol/Food/Lifestyle Interactions |
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Disease Interactions |
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First Approval Date |
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March 30, 2009 |
October 19, 2009 |
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WADA ClassView World Anti-Doping Agency classifications. |
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N/A |
N/A |
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More Information |
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Consumer Resources |
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Professional Resources |
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Related Treatment Guide |
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** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
For Breast Cancer: I have been taking Afinitor for about 2 weeks. Just feel I cannot continue in with it, feeling like my heart is racing for hours after taking it, it feels close to a panic feeling. No mouth sores(yet) doing the steroid mouth swish as ordered. However, I suddenly have a cluster of large pimple like sores on inner thighs, my skin in general feels very dry. I just cannot deal with sores and am terrified they will become wide spread. I was on Ibrance a year and then it stopped working. The only side effect was fatigue, that I can deal with but sores - no. calling my doctor and telling him the side effects are too much! Give me a med that has fewer serious side effects! I have not taken it long enough to evaluate if it is even being effective. Just no the side effects have begun right away.