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User Reviews for Effexor XR

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10
   
31%(62)
9
   
24%(47)
8
   
11%(22)
7
   
8%(16)
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4%(8)
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3%(6)
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5%(9)
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8%(16)

Effexor XR Rating Summary

7.5/10 Average Rating

200 Ratings with 162 User Reviews

What next?Compare all 222 medications used in the treatment of Depression.

Reviews for Effexor XR to treat Depression

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"I was on Effexor XR for almost 4 months for major depression and anxiety. It caused stomach upset which got worse with every increase in dosage.( I also suffer with IBS so it was hard to tell for a while if it was the Effexor or not.)The worst part however, was yet to come. I started spotting the 3rd month I was on it and by the 4th month on 150mg, I was bleeding as if I had my period every single day. My psychiatrist is tapering me off it and at 75mg now, I have less stomach pain and no bleeding. We will try Zoloft next."

   
1.0

Nika776 September 23, 2016

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"Male, 6'2", 150lb. I take 75mg of Effexor XR in the AM and 15mg of Remeron in the PM for suicidal depression and generalized anxiety. Some days I take higher doses of 112.5mg and 30mg. The combination has worked wonders for my condition. I started on Remeron initially and titrated to 45mg/day, but did not feel it was working for my depression, although it did help with sleep and appetite. I tried gabapentin for a while and was able to quit Remeron entirely for some time (wanted to give my receptors a break). Gabapentin was great for anxiety but made me more suicidal. I quit gabapentin and went back on just 15mg of Remeron, this time also adding the Effexor. I have been very happy with the results. It seems to be the first medication that really works for me. I had significant side effects when starting Effexor, but they subsided completely after about a week- feeling high much like MDMA, and I had diarrhea and some insomnia. When I increased from 37.5 to 75 mg, the only con I noticed was lower energy level (and some yawning). I started drinking some coffee to help with that. This is a very serious medication to be taking, as I know it can be very hard to withdraw from; however, I am committed to sticking with it. Eventually may increase my dose up to 150mg. Effexor makes me feel very mellow. I am less concerned about what people think of me. I am quite confident with the ladies. My sex life has been better than ever on this med combination. I have wondered if my sense of humor is dulled, however. I am also somewhat lazy, but this may change when I go up to a higher dose. Risk-taking behaviors should be watched when increasing the dose, as I broke my ankle playing sports. Overall, I give this medication 9/10 and am very happy that I got the script. I recommend taking it with Remeron to better manage the nighttime, and to counteract the side effects. They have a wonderful synergy. My only concern is that they may eventually stop working, and I may eventually have to stop taking them and suffer the infamous withdrawals."

   
9.0

Roger33 (taken for 6 months to 1 year) September 13, 2016

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"Adding just 37.5mg of Effexor to my 15mg of Remeron had quite an impressive effect for my depression and anxiety. I titrated to 75mg and have stuck with that for several months with great results. This is the first medication that I feel has truly worked for me. (In the past, I've taken bupropion, hydroxyzine, propranolol, gabapentin). The combination with mirtazapine makes for almost a perfect synergy. I feel that I have achieved true therapy and healing since I started taking "california rocket fuel"."

   
9.0

Duckyjwalker (taken for 6 months to 1 year) September 11, 2016

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"I have been on Effexor for over 5 years now and I cannot imagine life without it. I was crying all the time for no reason....my dr. Put me on 75 mg a day and it made me extremely anxious. He then upped it to 150 mg per day and I have no side effects and function great! The only side effect I have noticed is: if I forget to take it I start to feel dizzy after a few hours and by night am crying."

   
10

Bonfire Blast September 1, 2016

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"I started on the lowest dose about a year ago, I was use to taking my meds at night. Seeing I take 2 different meds for neuropathy, its just easier to remember to take all meds before bed. Well Effexor literally had me up for 2 days straight, so I contacted my doctor who said to start taking it in the morning. I am now on 225mg every morning, and am doing better. I do take it for depression, & anxiety which I have fought with since I was a teen. Effexor is the only one that has truly help, and I haven't giving up on."

   
9.0

Mjackson1981 August 23, 2016

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"I experienced a very low libido, very few erections, and dry orgasms."

   
9.0

Edward Barker (taken for 2 to 5 years) July 26, 2016

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"Didn't find it a whole lot different from SSRIs other than a couple weeks of jitters. Starts off with a contented, floaty feeling and then after a month subsides to having a minor, yet meaningful effect in helping me recover from recurrent depressive episodes. It helps, but only marginally. The withdrawal effects I've experienced going cold turkey off it numerous times are strange. A couple months of severe flu-like symptoms and I'll cry very easily over anything even remotely sad. Also causes me to start rapid-cycling between euphoria, mixed and extreme depression. Also lasts a couple months. Going off of it abruptly is quite terrifying. I recommend titrating off it."

   
6.0

Kyle BC (taken for 6 months to 1 year) July 25, 2016

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"Effexor XR really has been working wonders on my life. It has relieved me of a lot of my depression while still giving me my energy, unlike SSRIs. If weight gain is a problem for you and you have depression, definitely try an SNRI first. As you may or may not know, Wellbutrin is another antidepressant that is supposed to encourage weight loss while relieving depression. It affects norepinephrine and dopamine. I tried Wellbutrin awhile ago, and failed miserably on it due to the anxiety it brought on. Therefore, I was hesitant at first because I heard that Effexor XR affects norepinephrine as well. However, it has been completely the opposite. I have gone from constantly laying in bed all day long to wanting to get up and exercise."

   
9.0

Vin992211 (taken for 1 to 6 months) June 28, 2016

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"I wouldn't recommend this medication to my worst enemy. Although it seemed to work in a mild sense for my anxiety, when I missed even one dose, I paid dire consequences. I would wake up the next day dizzy, unable to see straight, started experiencing migraines, and would sweat day and night. I wish that my healthcare provider would have warned me of the detoxes before I accepted this treatment."

   
1.0

Anonymous (taken for 1 to 6 months) June 26, 2016

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"Made depression worst ,was not effective even at 150 mg. I got an understanding of why people become alcoholics or drug abusers on Effexor/Venlafaxine. I would lay in bed all day waiting for life to pass by. I never had feelings of despair so severe. If I mised a dose or waited for an hour later to take Effexor I had an intense "Rush". I would pace around like on cocaine or speed. You cannot stop taking this medication. I am still trying to get off it! When I reduced my dose I had a drunk effect with nausea I just felt so awful. I consider this to be a drug that shoudnt be prescribed. Celexa and zoloft "robot drug"worked well on me for anxiety and depression but I do NOT recommend this medication. Going back to Elavil"

   
2.0

ladybug33 June 20, 2016

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"I've been taking Effexor for about six months. within the first month I was up to 150mg. Since then I no longer have depression. I do have some moments of depression but not days/weeks. I do not have any panic attacks anymore! I'm not nearly as nervous as I was before Effexor. HOWEVER, my first week on Effexor was hell. I was extremely anxious, teeth chattering, night sweats, buzzing headache. and after months on Effexor if I miss one dose I get brain zaps. I'm also having vivid dreams. good dreams and bad ones. THIS MEDICINE TAKES TIME"

   
7.0

blondielocks June 18, 2016

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"primary care doctor started me on effexor xr 75, increased to 150 after 1 month. I was still very depressed and went to a psychitrist, crying at the first visit. she said it was melancholic and immediately doubled the dose to 300/day. It worked very well at the high dose, which I took for 4 years. it was more effective and continued to be the whole 4 years. best of all i had tried (paxil, celexa, lexapro, wellbutrin). i seemed to be in remission, we began tapering down. went to 150 for 1 month, then 75 for 1 month then stopped. i got the foggy feeling and "brain zaps" but a temporary increase in my klonopin dose for a week and i felt fine. i should mention i went through alcohol and opiate withdrawal before, so this seemed not that bad."

   
9.0

ewh75 June 17, 2016

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"Took first dose of 75mg before bed. Fell asleep at 1030 and slept well, actually. Woke up at 530 with eyes wide open as if i just had 10 espressos. It's now 630 and I don't have to be out of bed until 7. Can't sleep anymore. Feeling jittery with jaw clenching and teeth chattering when I open my mouth a little. Hands are sweating. I feel a little emotionally numb. Slight ringing in ears and slight headache with slight nausea. I feel peaceful but dull. Not sure if I will take again."

   
2.0

Lylalola84 June 1, 2016

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"I have been on effexor xr for 11 years now and it works wonderfully for me. The only side effect was dry mouth and constipation. It.s not for every patient. Always contact your doctor if your symptoms worsen."

   
10

depression/free May 28, 2016

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"I suffered depression and anxiety at a very difficult time in my life 5 years ago and have been on efexor 75mg since then... it took the edge off highly stressful situations and helped me to cope in a calm and positive way :) Life has been good since then, even though family problems have endured (thankfully to a lesser extent)... side effect of nausea was to be expected during first few weeks but after that no problems at all... effexor has been a wonder for me... :):):)"

   
10

pealove May 23, 2016

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"Horrific side effects and incredibly difficult to wean off of as well because of the withdrawal symptoms. When I first started taking it, I felt some relief but it didn't last very long. I'd taken Lexapro and Zoloft in the past and felt that, over time, they were no longer helpful in treating my depression which is why my doctor put me on Effexor. It took me a while to realize this medication was worsening my depression symptoms and I didn't realize it until after a botched suicide attempt. I don't recommend this medication to ANYONE for any reason. Worst of the worst as far as I'm concerned. It'll trick your brain for a little while into thinking you're improving but the depression and anxiety will come back and hit you ten times worse!"

   
1.0

cd87925 (taken for 6 months to 1 year) May 12, 2016

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"It should be ILLEGAL to prescribe this drug. I have tried most antidepressents and never have i experienced such atrocious side effects from withdrawing. I have never written a review on anything but i was compelled to share the experience. again, it should be illegal to prescribe effexor xl."

   
1.0

poppy271 (taken for 6 months to 1 year) April 26, 2016

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"Sadly only lasted 5 days on Effexor XR. The side effects from the 75mg dose was unlike anything I have experienced before. Within 10 hours of the first dose I had severe anxiety - something I had never experienced before. Within hours of second dose the extreme nausea came on. By day 3 I was pratically bed-ridden in cold sweats and feeling completely "out of it" . I persevered hoping the effects would begin to subside but by the 5th day I had severe nausea, couldn't get out of bed from feeling so sick, horrible tinnitus (ringing in the ears) and felt spaced out to the point that I began to wonder if I would ever feel "normal" again. Advised by GP to cease immediately on hearing my side effects."

   
1.0

Simesy (taken for less than 1 month) April 24, 2016

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"I was prescribed effexor for anxiety which interfered with sleeping - worry about getting to sleep meant that I wouldn't sleep which made me feel exhausted, depressed and useless. I've also tried Zoloft and Luvox which didn't do anything. CBT and mindfulness were also pretty useless - just made me slightly more obsessive about my weird problems with getting to sleep. Effexor has been amazing. Apart from some insomnia and lightheadedness during the first week I don't have any side effects. I don't have the same obsessive and weird anxious thoughts over getting to sleep or other minor things which preoccupied me and made me feel dreadful. I sleep well and my head feels so clear."

   
10

StephanieKandS (taken for 6 months to 1 year) April 20, 2016

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"I just wanted to die while going through withdrawal, while tapering off very gradually and for six months afterwards. Longer term effects are too painful to write about right now. Avoid."

   
1.0

Jane A April 17, 2016

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"I was put on effexor for severe depression at 75mg. This got raised every time it stopped working until I reached 225mg. I was on it for about 3 years. To be fair it worked really well the first 2 years. BUT, after the second year I went flat, felt No emotion at all, didn't care about anyone or anything. It was worse than the depression that I was originally treated for! Then came the time to get off of it. This was like hell! I have had to detox from opiates in the past and that was a piece of cake compared to this. It took me over a year to get off of it and ended up taking tiny beads until I was well enough to stop. If you can avoid this medicine do it!!"

   
3.0

Cricketk April 10, 2016

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"I have been on Effexor for about 6-7 years now. I started taking 75mg which needed to be increased to 4x 75mg per day as I was in complete terror. This drug saved my life. I would not be here if not for this drug. I tried Amitryptyline, citalopram, and propranolol for many years previously but they did not give me the relief I needed. 1st 2 weeks of taking this drug while off work, I saw the room flip upside down a few times making me fall down in the shower etc. It was a really scary time but once in my system I got great relief almost immediately. My side effects now are just sweating and tiredness but I am on 2 x75mg/day & feel really content. I got down to 75 mg/ day but felt anxious so upped to 2/day. Great drug if it suits you!!!!"

   
9.0

Nic (52) (taken for 5 to 10 years) March 13, 2016

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"1/10 would not take again. Felt dizzy nauseous and tired."

   
1.0

Marbling March 10, 2016

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"Used it during menopause for extreme emotional distress. That was 15 years ago. It was slowly increased from 33 mg to 225 mg due to ineffectiveness. I finally decided after reading up on it that it wasn't worth the side effects that I had if I ran out or if I wanted to get off. Well, I decided to get off. Please do not go on this drug if there is a chance you will ever want to go off of it. It took me 4 months to wean myself off. This past week was the first week I have been completely off. It has been an excruciating long 4 months. I took my time, but the withdrawal is bad. I can not imagine withdrawal from other drugs being much worse. Feel sick to my stomach, Joints ache beyond belief. Emotionally I am a mess, but I try, I try!"

   
5.0

Jeod (taken for 10 years or more) February 28, 2016

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"Gave me my life back. 150mg"

   
9.0

Anonymous (taken for 1 to 2 years) February 22, 2016

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