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Axiron and Sexual Dysfunction: What Users Say

Sexual dysfunction: mentioned by 6 users (6.3%)

Based on user experiences from 95 Axiron reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

fatigue 6.3%
sexual dysfunction 6.3%
moody 5.3%
tiredness 5.3%
burning 4.2%
headaches 4.2%
nausea 4.2%
anger 3.2%
depression 3.2%
weight gain 3.2%

Reviews for Axiron

Commonly mentioned side effects
  • Any...
  • Taken for less than 1 month
  • September 30, 2013

For Hypogonadism, Male "I had ZERO libido, weakness, lack of enthusiasm, kind of 'just existing joylessly.' Tested very low to below normal testosterone for a guy in his early 40s. After a few weeks on this, most of my symptoms are gone. Sadly, the libido has only improved a little bit. But my mood is improved, and it seems like my brain works better. The most surprising effect has been a rapid increase in muscle mass and improved muscle tone. Just 30 minutes of push-ups and work with free weights a couple of days a week has had amazing results. Exercise has never paid off like this. (Maybe I've been on the low end of testosterone all my life.) My only worry now is what will happen if my body compensates for the Axiron and reduces its natural T production."

8 / 10
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53 Report
  • J73...
  • Taken for 1 to 6 months
  • March 29, 2016

For Hypogonadism, Male "I am 42, and I have been on 60 mg Axiron for 6 weeks. Initial total T was 240, with all the symptoms of low T. Today, my total is 840 and free is 248. I feel fantastic. The first couple of days were tough as my body adjusted. The only downside for me is the minor alcohol irritation after application, but well worth it. Initially starting this medication, my skin was oily, libido was out of control, my facial hair seemed to grow in within minutes, I was retaining water, and my scrotum shriveled up. After a week or so, everything returned to 'normal'. No back hair or sudden muscle bulk. No gyno or roid rage. The product works great for me, and I was shocked as it seems everyone likes bashing the topicals and raving about injections."

9 / 10
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32 Report
  • and...
  • April 30, 2013

For Hypogonadism, Male "At 54, I had little energy by day's end. I was falling asleep in a chair after dinner. For the first time ever, my libido was diminished. I was moody and depressed. I also had problems concentrating at work. On 60 mg for a month, all symptoms turned around except libido. My doctor moved me to 90 mg. I have been on that dosage for 2 weeks and seem to have regular headaches."

8 / 10
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31 Report

Frequently asked questions

  • Bre...
  • Taken for 1 to 6 months
  • July 19, 2016

For Hypogonadism, Male "I had used testosterone injection therapy with mixed results. My doctor was concerned about possible heart attacks in an article he read, so he switched me to Axiron. I took it for 4 or 5 months. I did not find Axiron hard to apply, other than waiting 3 minutes between deodorant and application. Sometimes, I felt a bit warm as far as body temperature afterwards. The problem was, it didn't work for me. Sexual function got worse and worse, and I just had a blood test where my testosterone was 105, horrendously low for a mid-40's person. So basically, my body does not absorb it."

2 / 10
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16 Report
  • Ano...
  • Taken for less than 1 month
  • June 11, 2012

For Hypogonadism, Male "I am a 50-year-old male and pre-Axiron, testosterone tested out at 323 in the morning. I was feeling tired, sluggish, no sex drive, and falling asleep in the early evening. I started using 60 mg a day of Axiron. I noticed a huge increase in energy and increased libido during the first two days. Day three, I could feel the effects of Axiron tapering off, and I returned to feeling tired and sluggish. After one month of using Axiron, a morning test of my testosterone tested out at 257. Axiron dosage was just increased to 90 mg a day. I am not sure why Axiron would work initially and then stop working. I will give the 90 mg a day of Axiron a try for another month and have my testosterone re-tested."

2 / 10
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21 Report
  • Doe...
  • June 10, 2016

For Hypogonadism, Male "I have been using Axiron for 3 months and have experienced no noticeable positive effects. Still have low libido, no morning erections, lack of penile sensitivity, weak orgasms, and lethargy. Going to try injections ASAP."

1 / 10
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14 Report

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