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Axiron and Depression: What Users Say

Depression: mentioned by 3 users (3.2%)

Based on user experiences from 95 Axiron reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

fatigue 6.3%
sexual dysfunction 6.3%
moody 5.3%
tiredness 5.3%
burning 4.2%
headaches 4.2%
nausea 4.2%
anger 3.2%
depression 3.2%
weight gain 3.2%

Reviews for Axiron

  • and...
  • April 30, 2013

For Hypogonadism, Male "At 54, I had little energy by day's end. I was falling asleep in a chair after dinner. For the first time ever, my libido was diminished. I was moody and depressed. I also had problems concentrating at work. On 60 mg for a month, all symptoms turned around except libido. My doctor moved me to 90 mg. I have been on that dosage for 2 weeks and seem to have regular headaches."

8 / 10
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31 Report
  • bcw...
  • Taken for 1 to 6 months
  • August 27, 2012

For Hypogonadism, Male "For about 8 months or so, I had started to feel completely different than I had ever felt in life. Now at 53 years old, I don't expect to feel like 20, but I sure didn't want to feel dead either. No interest in things, no libido at all, depressed, moody, and didn't care. I had no energy... none! My first thought was it was thyroid related since I suffer from hypothyroidism and just thought the meds needed to be changed. My doctor and I discussed it, took the various blood tests, etc. The thyroid was fine, but my testosterone levels had fallen almost 200 points since the previous test about a year ago. So, my doc put me on a one-month trial of Axiron, and what a difference. Numbers up 100, no more complaints!"

9 / 10
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27 Report
  • KYB...
  • Taken for less than 1 month
  • December 3, 2016

For Hypogonadism, Male "OK guys, time out! I never thought I'd come to the defense of a consumer product, much less one that costs such an obscene amount of money, but: 1. There are a lot of guys on here complaining they had low testosterone (Low T) and giving their numbers before treatment. A large portion of them say Axiron took their numbers up into the 500 range. THIS IS WHAT THE DRUG IS SUPPOSED TO DO! If you're roughly between 348-1000, you're back to normal. Axiron worked. The fact that you still feel tired, or fatigued, or depressed is most likely due to other issues. I think there are too many guys on here expecting to take this drug and it to turn them into the Hulk, make them happy all the time, and provide for them sex whenever they want it."

8 / 10
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21 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.