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Axiron and Fatigue: What Users Say

Fatigue: mentioned by 6 users (6.3%)

Based on user experiences from 95 Axiron reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

fatigue 6.3%
sexual dysfunction 6.3%
moody 5.3%
tiredness 5.3%
burning 4.2%
headaches 4.2%
nausea 4.2%
anger 3.2%
depression 3.2%
weight gain 3.2%

Reviews for Axiron

Commonly mentioned side effects
  • Too...
  • December 21, 2011

For Hypogonadism, Male "Axiron seems to be working well for me. I am 35, and this is my first hormone replacement used, so I do not know about how the others might work for me. I am awaiting my first blood test results after 7 weeks of usage, but I feel honestly like a normal man again. I don't know how else to put it. My initial levels were at 140 prior to starting therapy, with zero sex drive that was impacting my marriage, fatigue, and loss of interest in normal 'fun' things. Within 3-5 days of starting Axiron, my libido returned to teenage levels, I have ample energy and interest in my normal hobbies again. The application is a little to get used to, but once I got it, I have no issues. Otherwise, it would have gotten a '10' from me. Thank you!"

9 / 10
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  • Anonymous
  • April 20, 2012

For Hypogonadism, Male "I'm 56, had little energy, slept a lot, and gained a good deal of weight. I have felt really good since I started Axiron. The change was immediate and dramatic. I look forward to taking it. My levels were very low, and after two weeks of using Axiron, the test showed the level was higher and the doctor was pleased. I feel a libido again, and I have a lot more energy. My appetite is way down too, not sure that's an effect. When I use the applicator, I hold it in one place against the skin for a few seconds before I move it around, then I slowly move it while pushing it in and out a little. Don't let it come off the skin, and it now runs down my body rarely. Hopefully it keeps working. I like it a lot."

10 / 10
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  • Anonymous
  • September 12, 2011

For Hypogonadism, Male "I have been using Axiron (60 mg daily) for two months now. Before I started, my testosterone level was around 430, which is a little low for a 40-year-old male (has been as low as 190). I was doing the injections, but the constant ups and downs were terrible. Needless to say, I was optimistic when told about Axiron, but it's proven to be short-lived. I had my testosterone level checked again last week, and it dropped to 217! I suspected something was wrong when fatigue started setting back in. Anyway, I went back to my doctor today, and he increased the dose to 120 mg daily. Will have my level checked again in 10 weeks. Hope it starts working."

4 / 10
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Frequently asked questions

  • KYB...
  • Taken for less than 1 month
  • December 3, 2016

For Hypogonadism, Male "OK guys, time out! I never thought I'd come to the defense of a consumer product, much less one that costs such an obscene amount of money, but: 1. There are a lot of guys on here complaining they had low testosterone (Low T) and giving their numbers before treatment. A large portion of them say Axiron took their numbers up into the 500 range. THIS IS WHAT THE DRUG IS SUPPOSED TO DO! If you're roughly between 348-1000, you're back to normal. Axiron worked. The fact that you still feel tired, or fatigued, or depressed is most likely due to other issues. I think there are too many guys on here expecting to take this drug and it to turn them into the Hulk, make them happy all the time, and provide for them sex whenever they want it."

8 / 10
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  • Anonymous
  • November 7, 2011

For Hypogonadism, Male "I have been on Axiron for about 3 months. The first month I only did one pump and noticed a big difference in energy and clarity. My T levels were at 395. However, the effects began to wear off, and the doctor asked me to go to 2 pumps instead. That helped for a while, but I believe the fatigue is coming back. I don't want to use a lot of this. I need to get my levels checked again, but after a month and a half, they had actually dropped quite a bit. I was also on steroids for a nasal issue, which I am sure didn't help."

4 / 10
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  • Ano...
  • Taken for less than 1 month
  • June 11, 2012

For Hypogonadism, Male "I am a 50-year-old male and pre-Axiron, testosterone tested out at 323 in the morning. I was feeling tired, sluggish, no sex drive, and falling asleep in the early evening. I started using 60 mg a day of Axiron. I noticed a huge increase in energy and increased libido during the first two days. Day three, I could feel the effects of Axiron tapering off, and I returned to feeling tired and sluggish. After one month of using Axiron, a morning test of my testosterone tested out at 257. Axiron dosage was just increased to 90 mg a day. I am not sure why Axiron would work initially and then stop working. I will give the 90 mg a day of Axiron a try for another month and have my testosterone re-tested."

2 / 10
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21 Report

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