Skip to main content

Imitrex User Reviews & Ratings (Page 2)

Imitrex has an average rating of 7.8 out of 10 from a total of 206 reviews on Drugs.com. 71% of reviewers reported a positive experience, while 14% reported a negative experience.

Reviews for Imitrex

Commonly mentioned side effects
  • Hey...
  • Taken for 2 to 5 years
  • June 16, 2013

For Migraine "Migraines have become my worst enemy over the past 4-5 years. Thank goodness for Imitrex. I started with the pills, then the nasal spray and have worked my way up to the shots (plus nausea medicines). The pills had the least side effects. The spray was vile-tasting, but fast-acting, and I could take it while working. When my headaches worsened, they added Botox and upgraded me to the injected version. I needed something that acted FAST so I could stay in the classroom. The downside to the injection is the head rush, change of heart rate, and the flushing feeling. When I inject, I have about 15-30 BAD minutes, then I kind of restabilize, and about an hour later, I usually feel better and capable of continuing to teach."

8 / 10
Was this helpful?YesNo
30 Report
  • Deb...
  • December 4, 2013

For Cluster Headaches "This is a miracle for me. Cluster headaches would put me out of commission for 2 days. Imitrex gets rid of the intense pain of my eye feeling like it might pop out of my head! The first few times I took it, I had side effects of the heavy feeling on my chest and in my muscles. After 3 times, I can take it with no side effects. I've only taken it 5 times, but it's still working great."

9 / 10
Was this helpful?YesNo
28 Report
  • Mar...
  • Taken for 1 to 2 years
  • October 8, 2018

For Migraine "I only use this when I am incapacitated from migraine pain (I get it behind my left eye and can’t open it, have a hard time walking/talking, and end up vomiting). It relieves the physical pain, and I am able to see, walk, and talk, but I am still pretty much down for the count. It says you can take it every 2 hours, but MAN, 1 dose and I feel it for the rest of the day. I get very drowsy, my eyes get droopy, and it feels like I’m walking underwater...or through thick honey. Everything feels so heavy. My speech is slower. I get waves of nausea. Once I take it, I’m home for the day—no way would I feel comfortable driving. The side effects can be tough for sure, but I will take them over the bad migraine pain any day. I am always thankful I took it, even if I have to be confined to the couch for 4-6 hours."

9 / 10
Was this helpful?YesNo
19 Report

Frequently asked questions

  • Clu...
  • June 30, 2016

For Cluster Headaches "Words cannot express how grateful I am for this medicine. I have dealt with these crippling headaches since my mid-20s. Now in my mid-30s, I finally happened upon a physician (at a CareNow of all places) who actually listened to me as I told him of the nightmare I face at least three times a day, every day, for months on end, and prescribed Imitrex for me. If taken at the very first sign of an attack, these little beauties (I take the oral) can save you 30 minutes to several hours of unimaginable pain. I cannot recommend enough that my fellow cluster headache sufferers ask their doctor about considering Imitrex. While there's no cure, this is the closest thing I've found so far that at least makes living with these headaches bearable."

9 / 10
Was this helpful?YesNo
22 Report
  • Mar...
  • January 22, 2012

For Migraine "I hated my experience with Imitrex. It made my chest feel strange, heart beat increase, and I felt very anxious while on it. I guess it shortened the duration of my headache, but I became very worried and preoccupied by its side effects."

3 / 10
Was this helpful?YesNo
29 Report

Are you taking this medicine?

Your review helps others make informed decisions.
Write a review
  • Jun...
  • May 23, 2014

For Cluster Headaches "Imitrex works very well for my eyeball pain, light and odor, toxic smells, nasal stuffiness that leads to migraines. Migraines. I am sensitive to gluten of all kinds, if I ingest some, I WILL get nasal stuffiness that will lead to a migraine or cluster headaches. Imitrex works in 45 minutes, sometimes sleep is needed to take it away. Sometimes I get migraines for a week or so. Sometimes I take it as a last resort, after trying allergy meds, Tylenol, or Valium. But Imitrex works for me. I eat very healthy, no breads of any kind, no gluten, very little sugar. I read all labels, eat mostly veggies and meat, mostly organic, I'm getting better at that."

10 / 10
Was this helpful?YesNo
28 Report
  • Ste...
  • August 5, 2013

For Migraine "Imitrex has truly been a miracle for me. I'm 36, and I've been having terrible headaches since as far back as I can remember. No over-the-counter medication ever made any difference in the pain at all. Five years ago, I was prescribed Imitrex, and it has literally changed my life. It normally takes an hour or two for it to kick in for me, but when it does, it completely takes my headache away. I have never had any side effects either."

10 / 10
Was this helpful?YesNo
25 Report

More FAQ

  • Mom...
  • Taken for 2 to 5 years
  • June 14, 2013

For Migraine "I have migraines that are hormonal in nature, and Imitrex has saved me from days' worth of pain many a time. I also have a grade-school daughter, and if I have a migraine, believe me, the entire family suffers. The pain from a migraine can last 3 days for me, so having something that will knock it out in a matter of minutes is, in my eyes, miraculous. It doesn't ALWAYS work, especially if I have cluster headaches, but 90% of the time, it works for me on one dose. If the first dose doesn't work, I take another, and that usually just completely wipes it out."

10 / 10
Was this helpful?YesNo
26 Report
  • RCC...
  • May 29, 2015

For Migraine "Saved my life. Nothing else worked. Other drugs intensified the headache. I much prefer the injection. Less of the drug is needed, and the effective result occurs more quickly. Side effects - I can get night sweats and have 'odd' dreams that do not otherwise occur."

10 / 10
Was this helpful?YesNo
21 Report
  • ber...
  • Taken for 5 to 10 years
  • December 15, 2013

For Migraine "I have suffered from debilitating migraines for over 20 years. I feel like I have tried everything. Imitrex shots gave me my life back. After taking a shot, I normally need to lie down for 15 min, but then I feel great. I used to suffer for at least 3 days. I never had any side effects."

10 / 10
Was this helpful?YesNo
23 Report
  • Con...
  • Taken for 6 months to 1 year
  • April 30, 2018

For Migraine "I have had menstrual headaches, so predictable for 10 years. Once a month, 36 hours or so, can't even lay on my head, migraines. Just suffered through. Tried Imitrex last December and feel like I've been freed from bondage. I don't get a high or sleepy sensation, just relief, especially when taken with 2 Advil. I do not have ever used prescription pain meds. Seldom use even any NSAIDs. I was not interested in pain meds, so this was a great option and a miracle. I can even take 2 without side effects. Sorry to those who have poor outcomes. FYI, I was discussing it today with a colleague, and she said she felt high and loopy. I was stunned. Now, in reading this, I see some people do react that way. So I guess I would say, take half, at home with someone around. Then make a choice from that result. Good luck!"

10 / 10
Was this helpful?YesNo
15 Report
  • Anonymous
  • January 8, 2012

For Migraine "At first, I thought it was great-no headache. Then, the more frequently I used the medication to treat my migraines, the more debilitating side effects I began to experience. I could first mitigate the burning pain and weakness in my head, neck, and jaw and the general feeling of malaise and fatigue by the administration of Naproxen or Ibuprofen prior to the Imitrex, but then, even that ceased to be effective. I finally quit after experiencing total body weakness, a more severe burning pain in my upper extremities than ever before (accompanied by fluctuating hot and cold sensations everywhere else), irregular heartbeat, and irregular breathing after administration. If you experience adverse side effects, it gets worse! Please, find something else."

2 / 10
Was this helpful?YesNo
25 Report
  • Anonymous
  • October 15, 2009

For Migraine "Something that really works for me when my schedule allows is to take a short nap after taking Imitrex. I wake up with little discomfort. My head is clear. I can think. One of the worst symptoms of my migraines is that I cannot stay focused on a task. If I am unable to nap, the Imitrex has little effect on me. This is horrible when you are at work, as many of you know."

8 / 10
Was this helpful?YesNo
28 Report
  • Kdh...
  • Taken for 1 to 6 months
  • June 20, 2018

For Migraine "I have had migraines (growing blind spots, with nausea and pain) and also tension migraines since childhood. Starting with my third child, I started getting debilitating migraines. I’m talking, tingling fingers, trying to talk but my brain can’t find my words, pain that lasts at least 2 days with 1-2 of my brain not working. I tried Fioricet, and it didn’t work. Magnesium aspartate supplements helped a ton with the tension and blindness headaches. Finally, my doctor gave me this, and OH MY GOSH, 30 mins later I felt so much better, by an hour, it was gone! I still feel like my brain is dulled for several hours, but even though I can no longer feel the headache, it’s still there messing stuff up. On occasion, I have to take two. If I let the pain get really bad before I take it, it takes longer to work. I can usually count on it being gone for 6-20 hours before I need to take it again. I love it. Yes, neck stiffness, some jaw tightness... a million and twelve percent better than a migraine, though."

10 / 10
Was this helpful?YesNo
14 Report
  • Bee...
  • September 16, 2017

For Migraine "I am perimenopausal, age 53, and for the last several years, suffered from debilitating migraines. I wasted days because I was too sick from these headaches. Forget Excedrin for migraines or any other OTC drugs, no relief whatsoever. This past weekend, I had a migraine that pretty much knocked me out - the pain was horrific, nausea, vomiting, and I cried like a baby. Finally, I went to the emergency room, and they gave me Imitrex. Within 30 minutes, the headache was gone. I was very sleepy, but I don't know if that's a side effect or just from not sleeping the prior 3 days."

10 / 10
Was this helpful?YesNo
15 Report
  • jaq...
  • September 21, 2013

For Migraine "The only medication that works for my migraines, that last typically 3 days at a time, right side of my head, in my eye, down the back of my neck and upper back. I take the 100 mg tablet, 1 every 12 hours, or when I feel it coming back on. Imitrex kicks in within 20 minutes of taking it. As close to instant relief as you can get. GREAT medication."

10 / 10
Was this helpful?YesNo
22 Report
  • Min...
  • July 7, 2017

For Migraine "I preferred Relpax, but my insurance stopped covering it. Imitrex works at least 95% of the time, but maybe 10% of those times, the headache recurs and I have to take another one (which almost never happened with Relpax). My side effects are weird but not debilitating: sense of pressure in head, neck, chest, shoulders, arms; tingling in face; dry burning eyes; skin sensitivity to hot/cold; taste sensitivity to spicy/sour; lack of appetite; sweat; thirst; diuretic. A bit sluggish and sometimes drowsy, but not truly fatigued. Almost never nauseous; never dizzy. A couple of hours later, I often feel mild muscle soreness. The side effects are stronger if I take it on an empty stomach, but it also works faster."

7 / 10
Was this helpful?YesNo
16 Report
  • Phi...
  • February 19, 2017

For Migraine "Works great, the only one for me, no side effects, 53 yrs old, started getting these headaches last yr, Excedrin, aspirin, Fioricet, and Advil didn't work, takes about an hour to kick in, but since nothing else works, I can wait it out."

10 / 10
Was this helpful?YesNo
17 Report
  • Anonymous
  • Taken for 10 years or more
  • June 23, 2012

For Cluster Headaches "I suffered with cluster headaches for about 15 years before finally receiving an Imitrex injection in the hospital ER. My headache was gone within 5-10 minutes, I thought it was a miracle. I do not leave home without it!"

10 / 10
Was this helpful?YesNo
23 Report
  • Mam...
  • Taken for 6 months to 1 year
  • December 21, 2016

For Migraine "I have suffered migraines maybe four times a year or so since I was little. Usually accompanied by vomiting and complete inability to function. The past two years, after having my second daughter, the migraines have amped up to three or four a month-sometimes more. Imitrex works almost always to eliminate the migraine. Every once in a while, I wait too long and have to take two. I have no side effects to speak of, which is crazy to me because I can't even use herbal remedies without experiencing weird side effects. I'm thankful for the scientists who created this drug. I always have it with me just in case, and it keeps me from being out for the count with my two little girls."

9 / 10
Was this helpful?YesNo
16 Report
  • ano...
  • Taken for less than 1 month
  • August 4, 2014

For Migraine "Imitrex did not work for me. I have not reached the vomiting stage of a migraine in years thanks to other medications. Imitrex did nothing to stop the progression of my migraine. I had to leave work in the middle of the afternoon, feeling as if I would vomit at my desk, in the hallway, in the elevator, walking to the parking garage, the entire way. Aleve works better than this stuff, and Aleve only keeps nausea at bay, but does not cure migraines for me."

1 / 10
Was this helpful?YesNo
28 Report
  • Eri...
  • Taken for 5 to 10 years
  • September 7, 2017

For Migraine "Reading some of these reviews makes me wonder how much of a chance they gave the medication. I've had 'vascular' migraines since I was 13. I'm 35 today. I take Excedrin migraine for my headaches. I take Imitrex for my migraines. It used to be hard to tell the difference. I understand now the difference. But before I found Imitrex, I took all kinds of 'prevention' meds: amitriptyline, nortriptyline, Zoloft, more than I can remember. Never prevented a darn thing. Just ended up with side effects from those. As a teen, that meant acne and weight gain. Aka, hell. It's been years now since I've found Imitrex. And like many, I was worried about trying it. But there came a day I couldn't NOT try it. Twenty minutes later, I kicked myself for waiting."

10 / 10
Was this helpful?YesNo
15 Report
  • Jen...
  • October 18, 2019

For Migraine "I almost always get migraines around my period or times of extreme stress. I was getting a migraine that began as nausea, hot flashes, dizziness, and weakness the entire day. That night the pain started, so I took 25 mg Imitrex. In 90 minutes, the pain was gone. I felt some pressure where the pain had been and couldn’t lay on that side. A week later, I feel another migraine come on, and I wasn’t sure it was a migraine until the nausea came. I took Imitrex again, and the pain went away after 2 hours, but then I got super drowsy and fell asleep and woke up an hour later shaky and anxious. I had not had a good night's sleep the day before, so those symptoms may be attributed to lack of sleep, but they went away after a few hours. I did try Imitrex in the middle of a migraine with nausea, blurry vision, severe pain, and it didn’t help. I was discouraged and did not take a second dose that time. I suggest taking Imitrex as soon as you feel pain."

9 / 10
Was this helpful?YesNo
11 Report
  • Anonymous
  • Taken for less than 1 month
  • September 10, 2012

For Migraine "The first time I took this, I got a severe panic attack. It felt like I couldn't breathe, my heart was racing and chest hurt. It did nothing for the pain or any of the other things associated with migraines. I did try it once more, as per my doctor, and it happened all over again. Maxalt is what I use now."

1 / 10
Was this helpful?YesNo
21 Report
  • Sle...
  • Taken for less than 1 month
  • April 29, 2016

For Migraine "I was diagnosed with severe, painful, and silent migraines a few months ago, but the neurologist said I've most likely suffered from silent migraines my entire life (I'm 17, by the way). Recently, they have started getting painful. Imitrex was the first medication I was put on. I was excited to start feeling better, but Imitrex made me feel awful. I suffer from extreme nausea before, during, and after a migraine, and it's completely life-ruining. I've tried Imitrex many times in hopes of it finally working. Every time I'd take it, I'd get a horrible burning in my throat, and my migraine would worsen. It didn't help nausea, aura, pain, or any other migraine symptoms I suffer from. I've recently been put on another medication that'll hopefully work."

1 / 10
Was this helpful?YesNo
16 Report

Are you taking this medicine?

Your review helps others make informed decisions.
Write a review
Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.