Ropinirole and Sick: What Users Say

• UPS...
• October 24, 2016

Ropinirole for Restless Legs Syndrome "It works, but it's based on what is in your stomach. If I'm stuffed and ate too much before bed, which can be hours before bed, I need 3 mg. Somewhat full, 2 mg, and if I ate small meals and I take it 2 hours before bed, 1 mg. Now if I take 1 or 2 mg on an empty stomach, I might feel sick. I have gotten home before, after work, and very hungry and ordered pizza. Took 1 or 2 mg before ordering and felt sick before the pizza even got here. So the mg's need is based on what's in your stomach. It works great, but you can't just take what the doctor says, like 2 mg before bed, because it changes. Have the doctor give you 90 tablets at 1 mg and write 'take 1-3 per night as needed.' We'll see if that helps, and I feel your pain."

• Sho...
• Taken for 10 years or more
• August 31, 2019

Ropinirole for Restless Legs Syndrome "Wonderful, especially the extended release. Generic makes me deathly nauseous. Requip is a miracle. Have had RLS since 10 years old. I am 63. Wocart stopped making generic that did not make me sick. Had to go to the brand name. Made me sick first 2 nights. Now the miracle for me."

• Sho...
• January 21, 2015

Ropinirole for Restless Legs Syndrome "My restless legs syndrome has become really annoying in the past few months. I was on Gabapentin, which seemed to help, but it started to become less effective, so the Dr. switched to Requip. On my first night, I felt sick and had flu-like symptoms. The next day, I took it early and immediately felt sick and started to throw up and felt chills and then felt hot. This medicine did absolutely nothing for me besides make me sick."

• Anonymous
• February 6, 2020

For Restless Legs Syndrome "I started taking a 3 mg dose of ropinirole at night for my restless legs. I've had horrible restless legs for the past 2 years since I had my daughter. An hour after I took this medicine last night, I was very nauseous and started throwing up. I didn't have restless legs last night, but I was very sick for about an hour. I'm trying this medication one more night to see if I can get by without getting sick. If I do get sick again, I'm going to only take half of the medication next time."

• Jac...
• Taken for less than 1 month
• September 6, 2019

For Restless Legs Syndrome "So I am now 46 years old and have severe RLS, which is getting worse over at least 20 years. I started on ropinirole, and I was very sick at first on 1 mg, I stuck with it, and after 5 days, it stopped. I was taking 2 mg per day, but after a couple of months, I started getting worse - I suffer from bad legs and arms, and then my whole body gets taken over by this disease! So I am now on SLOW RELEASE 4 mg, however, I feel awful every night - like I am full of the flu, feeling sick. I wondered if the fact it's a different brand may make a difference... Anyone else have this issue?"

• Jac...
• Taken for less than 1 month
• September 6, 2019

For Restless Legs Syndrome "So I am now 46 years old and have severe RLS, which is getting worse over at least 20 years. I started on ropinirole, and I was very sick at first on 1 mg, I stuck with it, and after 5 days, it stopped. I was taking 2 mg per day, but after a couple of months, I started getting worse - I suffer from bad legs and arms, and then my whole body gets taken over by this disease! So I am now on SLOW RELEASE 4 mg, however, I feel awful every night - like I am full of the flu, feeling sick. I wondered if the fact it's a different brand may make a difference... Anyone else have this issue?"

• Bee...
• Taken for less than 1 month
• November 28, 2018

For Restless Legs Syndrome "So... after years of failed drug 'trials,' my consultant said I was now severe, so has put me on Ropinirole. The 1st night felt sick but fought it off, but last night... WOW!! It was like a scene from the Exorcist!! That sick flew out of me... within an hour!! Then afterward, I was feeling really weak but fell asleep pretty quickly and woke up at 6... a bit zombified though!! I DID fall asleep at my desk... literally 5 mins, but was unexpected!! More updates to follow... can any fellow sufferer tell me if the sickness wears off... pleassssee!!!"

• bet...
• Taken for less than 1 month
• April 21, 2017

For Restless Legs Syndrome "Prescribed ropinirole by hospital doctor for RLS that began while in hospital for subdermal hematoma due to a fall. RLS does not always last a lifetime. Anyhow, Dr. prescribed it to me upon leaving the hospital. I started to take it as prescribed, but it made me feel ill and awkward, so I stopped. My OT then asked why I wasn't taking it and advised me to 'take as doctor ordered' despite the bad experience. So, I started back on it. By 3 weeks, it was slowing my movements to a snail's pace! It took me 30 minutes to walk 30 feet, it was horrible! My family came to realize the reason for my near paralysis was this new drug. We are ready to sue and hope it doesn't cause permanent walking difficulty! I walked out of the hospital just fine, now this?! USE CAUTION, folks."

• KRL...
• January 7, 2016

For Restless Legs Syndrome "I have been taking ropinirole since April, and while it works well to relieve my RLS symptoms, it still makes me sick about 50% of the time. The first night I took the whole 1 mg pill and became violently ill. Cold sweats, nausea, vomiting. I then started cutting the pill in half, making sure I ate a piece of bread with it and waiting until at least 2 hours after I had taken my nightly (necessary) melatonin and sleep aid capsule. That seemed to work, but I soon found out it was hit or miss. I have been awakened several times now, sometimes within an hour, sometimes a full 5 or 6 hours after taking it, with shaking, sweating, and horrible nausea. So now I only take it when I am absolutely positive the RLS is going to be relentless."